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Bicalutamide
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Bicalutamide

Bicalutamide is an oral medication that is used for treating cancer of the prostate. It belongs to a class of drugs called anti-androgens which includes flutamide (Eulexin) and nilutamide (Nilandron). Androgens (an example of which is testosterone) are hormones that are produced and released by the adrenal glands. They are responsible for supporting (stimulating) tissues that primarily are thought of as male, for example, the male prostate gland. Male traits that also are influenced by androgens include facial and body hair, and small breasts. Anti-androgens prevent the action of androgens by blocking the receptors for androgens on the cells of tissues, for example, the cells of the prostate gland. In addition to normal prostate cells, androgens also have been shown to stimulate the growth of cancer cells within the prostate. Bicalutamide is thought to prevent the growth of prostate cancer by blocking the effects of androgens on the cancer cells. Bicalutamide was approved by the FDA in 1995.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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A study of the increased incidence of institutional delivery, the adequacy of existing obstetrical facilities, and a survey of present obstetric and gynecologic clinics in Sweden and Finland The global health concept of the German government: strengths, weaknesses, and opportunities. Osteoformin decreased the healing time of fresh fractures in rats, as indicated by histologic and radiographic assessments. Prospective independent validation of APACHE III models in an Australian tertiary adult intensive care unit.

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A nationwide intervention was launched to contain the outbreak and to introduce a strategy to control future dissemination of antibiotic-resistant bacteria in hospitals. The A19 transcript is non-coding and expressed in mouse testis and brain. It should be stressed, however, that the effect of hormone stimulation or aromatase inhibitor action appeared to be dependent on the length of light cycles that bank voles were exposed prior to the isolation of Leydig cells. Overall, 79 samples were successfully assayed for DISH using the series of optimization protocols.

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However, an understanding of the evolutionary relationships among the three modern-day classes of ribonucleotide reductase and how the first reductase arose early in evolution is still far off. Uterine fibroid in a man: how African tradition solved a social crisis. Laboratory observations on pupation and emergence in the mosquito Aedes (Stegomyia) aegypti (Linnaeus). Measles outbreaks in 1999 in Queensland and Victoria, Australia, were caused by a novel strain of clade G virus (proposed name g3).

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These results suggest that primate XNA recognize similar antigens on rat and pig ECs. Once the diagnosis of congenital nonhemolytic hyperbilirubinemia is confirmed, patients should be informed of the disease process and its benign nature to prevent needless work-up in the future. In morbidly obese patients with pulmonary hypertension, right ventricular systolic time ratio is a valid index of contractility. Stereospecific effects of ketamine on dopamine efflux and uptake in the rat nucleus accumbens. EEG coherence and symptom profiles of children with Attention-Deficit/Hyperactivity Disorder.

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There are, however, numerous other causes of a mild to moderate homocysteinemia, for example, a deficiency of the cofactors vitamin B6, B12 and folic acid. Gender preferences and demand for preconception sex selection: a survey among pregnant women in Pakistan. The vaginal pessary is a safe and effective method for the correction of uterovaginal prolapse.

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The surface properties and structure of a biomaterial play an essential role in protein adsorption. The spider mite genome has been sequenced and its transcriptional responses to developmental and various biotic and abiotic cues have been documented. COMPARATIVE STUDY OF AN IMMUNOLOGICAL PREGNANCY TESTS AND THE FROG TEST For 3/6 tumours we found differences between control groups and treated animals. A total of 232 CHD patients and 93 healthy persons were examined to reveal a possible role of the vasospastic and cardiohemodynamic factor in the pathogenesis of angina pectoris of various duration.

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Size limitations governing the incorporation of genetic material in the bacterial transformations and other non-reciprocal recombinations. In situ hybridization and immunohistochemistry gave similar results for serial sections from each of 15 lung samples. Oxygen affinity of hemoglobin solutions modified by coupling with NFPLP and the effects on tissue oxygenation in the isolated perfused rat liver.

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During an extracardiac conduit type of Fontan operation, fenestration is not always technically easy, particularly when the right atrium is small and located posteriorly. On April 1, 1998, the Massachusetts Department of Mental Health established the forensic transition program for mentally ill offenders.

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A second potential source of sensory input on the CPG is derived from sensory signals related to hip position. The inhibitory effects of 40 extracts prepared from 38 traditional Turkish folk medicines on human aldose reductase (h-AR) and hematological activity were investigated.

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Hyaluronidase may be more important than previously suspected in preventing anesthetic-related damage to the extraocular muscles. Although recent studies suggest that gastro-oesophageal reflux disease (GORD) may contribute frequently to ear, nose and throat (ENT) and respiratory diseases, the cause-and-effect relationship is far from proven. Strong association of HMB-45 expression with renal angiomyolipoma. To determine the role of MRG15 in cell cycle progression we performed chromatin immunoprecipitation with an antibody to MRG15 on normal human fibroblasts as they entered the cell cycle from a quiescent state, and analyzed various cell cycle gene promoters.

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By comparing these MPSS libraries to those of 87 other tissues included in the Mouse Reference Transcriptome online resource, we have identified genes that are highly enriched in, or specific to, the inner ear. Discovery of protein acetylation patterns by deconvolution of peptide isomer mass spectra.

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Despite the initial success of androgen-deprivation therapy, PCa inevitably progresses from being androgen dependent (AD) to androgen independent (AI), and this marks the poor prognosis of this disease. With Ac-S16, a control-scrambled peptide, the only significant inhibition of the leukaemic infiltration was observed in bone marrow at a much higher dose. The etiology of urogenital fistulae in India seems to be changing to one in line with developed countries.

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We aim to review the literature regarding modalities of treatment to guide the management of AMNs. We review recent studies using new parameters to diagnose abdominal wall defects in the first trimester and to provide early prenatal counselling to parents regarding prenatal and postnatal prognosis. We first evaluated the effect of UNLM by assessing the modulation transfer function (MTF) and Weiner spectrum (WS) of UNLM in simulated imaging. Vascular disease: a new way to starve vascular endothelial cells. The utility of combining these methods in the study of modernization and blood pressure is illustrated by recent research in Brazil.

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In situ fluorometers were deployed during the Deepwater Horizon (DWH) Gulf of Mexico oil spill to track the subsea oil plume. These compounds are lethal to both the extracellular stage of the organism, which is inoculated into humans by the sand fly, and the intracellular stage, which is found solely in human macrophages during established infection. This prospective study included 4 patients who were diagnosed with PPS tumors and treated with the endoscope-assisted transoral approach. Skin biopsy specimens were collected from the dorsolateral thorax of 31 alpacas with normal skin.

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When dehydroepiandrosterone was administered to diabetic rats, the improved oxidative imbalance and the marked reduction of AGE receptors paralleled the reduced activation of nuclear factor kappaB and the reduction of S-100 levels, reinforcing the suggestion that oxidative stress plays a role in diabetes-related neuronal damage. Microsurgical treatment and prevention of postoperative complications for the fourth ventricle tumors in adults Salvia miltiorrhiza could induce hBMSC to differentiate into neuron-like cells. Interaction of ILK with beta 1-integrin subunits was investigated by coimmunoprecipitation and the role of ILK in regulating alpha 2 beta 1 function assessed by overexpression studies in HEL cells.

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Enhanced T1-weighted image showed marked enhancement of the mass. To conduct a serological survey of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in Gabon and Ga-Rankuwa, South Africa.

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Information about the patient population, the proportion of cases detected and treated by attending physicians, the length of follow-up, the affective outcome and the prognostic factors was abstracted from each report. We have tested this hypothesis under physiological conditions through use of a procedure that captures Golgi enzymes in the ER. The compound can also be used for the induction of anaesthesia in combination with analgesics.

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The effect of ascorbate and alpha-tocopherol supplementation in vitro on DNA integrity and hydrogen peroxide-induced DNA damage in human spermatozoa. Myc synergizes with Ras and PI3-kinase in cell transformation, yet the molecular basis for this behavior is poorly understood. Laparoscopic Appendectomy in Children: Preliminary Study in Pediatric Hospital Albert Royer, Dakar.

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Combination of Photoinduced Alignment and Self-Assembly to Realize Polarized Emission from Ordered Semiconductor Nanorods. The nervous plexus is also noticed along the terminal arterioles. Transgenic mice have been constructed expressing high (CD45RABC) and low (CD45R0) molecular weight CD45 isoforms on a CD45-/- background. Although policies to reduce air pollution should be based on the best available scientific knowledge, political will and capacity must transform this knowledge into action. A new study from daSilva and colleagues shows that in plant cells, individual Golgi always form adjacent to an existing ERES, and that an ERES and its associated Golgi stack move as a single secretory unit.

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The SEM analysis show for the cornea treated with the modified trephines a subjectively smoother surface. With the aim to determine the genealogy of the overlap, the codon usage of the overlapping frames P and S was compared to that of the non-overlapping region. These findings indicate that both MAD and CPAP result in similar beneficial changes in cardiac autonomic function during daytime, especially in blood pressure.

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Considering BMP2 mRNA expression was higher in MK-7-administered cells than in control cells, the effect of MK-7 administration on the signal transduction system was examined. Implementation leads to timely critical interventions and may reduce mortality. Diagnostic and therapeutic problems of the acute phase of poliomyelitis

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Each configuration was assessed using objective functions that represented different correction objectives. Clusters of measles cases in Jewish orthodox communities in Antwerp, epidemiologically linked to the United Kingdom: a preliminary report. Preliminary data suggest that inhibition of the sympathetic nervous system may be helpful, and inhibition of vasopressin in animals with heart failure is being studied. There was significantly less blood loss in group I (MIAS), as compared with the other 2 groups, but intraoperative blood transfusion for all groups was not significantly different.

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Water soluble proteins (WSP) in broad beans, Vicia faba, were purified, and their scavenging effects on free radicals and active oxygen species were investigated. Furthermore, both Lec3.2.8.1-produced and Chinese hamster ovary-produced CD8 homodimers and heterodimers were active in the inhibition assay.

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Comparison of two methods for concentrating stem cells for cryopreservation and transplantation. Optimizing targeting strategies for vectors in order to enhance antitumor activity and secure patient safety is important for cancer gene therapy. This is a survey study designed to assess the current use of MP in ASCI in Poland. Blood flow recovery in the extremities aggravates these changes leading in 12-hour ischemia to acute renal failure. In this study, we have reported that curcumin induces significant DNA damage in human papillary thyroid carcinoma BCPAP cells in a dose-dependent manner as evidenced by the upregulated phosphorylation of H2A.X at Ser139, which was further confirmed by the long tails in the comet assay and the increase in the number of TUNEL-positive cells.

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Elimination of the bases sodium hydroxide and potassium hydroxide decreases production of these noxious compounds without materially decreasing the capacity of the remaining base, Ca(OH)2, to absorb carbon dioxide. Diastolic performance assessed by tissue Doppler after pediatric heart transplantation.

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Cell replacement in the epidermis and sebaceous glands of the mouse. Non-pyridine nucleotide dependent L-(plus)-glutamate oxidoreductase in Azotobacter vinelandii. Thermal instability in the endoplasmic reticulum of the rat hepatocyte.

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Because actinomycin D was dispersed mainly in cytoplasm and Shc peptide (synthetic 13 amino acid tyrosine phosphorylated polypeptide) successfully displaced actinomycin D binding to its cellular targets while the other polypeptide from PDGF receptor could not. The removal of oxidized bases is performed predominantly by the base excision repair (BER) pathway and it has been shown that induction of DNA repair genes occurs in response to oxidative stress. Glycosaminoglycan composition was measured by enzyme digestion and nitrous acid deamination. It is important to recognize this serious infection in children with fever, since delay of diagnosis and treatment may result in serious complications.

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Clinical practice guidelines on the initial assessment and treatment of urinary incontinence in women: a US focused review. The repressive function of RIP140 results from its ability to bridge NRs to repressive enzyme complexes that modify DNA and histones.

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Highly Efficient Inverted D:A1:A2 Ternary Blend Organic Photovoltaics Combining a Ladder-type Non-Fullerene Acceptor and a Fullerene Acceptor. However, the need and safety of anterior reconstruction of the vertebral body defect remains unclear.

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Examination of vascular permeability using monastral blue showed that vascular permeability of the small intestine, lung and liver was clearly increased in TVO. A QUANTITATIVE STUDY OF THE BACTERIA IN CITY DUST WITH SPECIAL REFERENCE TO INTESTINAL AND BUCCAL FORMS. A novel fluorescent substrate was devised for the sirtuin (SIRT) class of human protein deacetylases comprised of a peptide sequence containing a single acetyl-lysine residue, with a fluorescent group (tetramethylrhodamine-6-carboxylic acid, 6-TAMRA) near the carboxyl terminus and a nonfluorescent quenching group (QSY-7) near the amino terminus.

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An example of such a tissue with predetermined shape is realized by fabrication of a tubular endothelial cell construct. Our study provided an insight into the fate and the behavior fluorescent DOM components for an MBR system, which could be an indicator of the membrane fouling. New technologies have improved early detection and optimal management of dystrophinopathies and have established the basis for future molecular medicine. Natural killer T cell ligand alpha-galactosylceramide inhibited lymph node metastasis of highly metastatic melanoma cells.

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The present investigation was undertaken in order to study how well estimated glomerular filtration rate (eGFR) using the new CKD-EPI equation correlates with measured GFR (mGFR) by (51)chrome ethylene diamine tetraacetic acid ((51)Cr-EDTA) clearance in a group of patients with cancer not known as having cancer. Cerebral intracellular lactic alkalosis persisting months after neonatal encephalopathy measured by magnetic resonance spectroscopy.

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Several representative genetic recombinants were isolated and shown to replicate equally well at the permissive (31 C) and nonpermissive (38 C) temperatures and to have serological characteristics of the wild-type parental virus. We present the case of a 42-year-old woman with an incidental finding of a large right adnexal mass during pelvic ultrasound scan for a spontaneous miscarriage.

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Here we show that the application of the GABA receptor blocker picrotoxin unmasks a robust excitatory OFF response in ON DS ganglion cells. Because the observed vaccination-induced lesions are detrimental to epithelial integrity and function as a barrier against invading microorganisms, they might explain at the ultrastructural level the secondary complications of vaccination with the La Sota strain against NDV.

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This study examined the efficacy and molecular mechanisms of exogenously delivered inhaled CO in protecting liver grafts from cold ischemia/reperfusion (I/R) injury associated with liver transplantation. Effects of iproniazid and similar compounds on the gastrointestinal tract. The course of the disease was favourable after treatment with intravenous ceftriaxone. We therefore assessed the prevalence and disease-related distribution of A1AT heterozygosity in the largest cohort to date for this purpose. Fusarium wilt is one of the most prevalent and damaging diseases of tomato.

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The presence of anti-MICA Abs could be an important marker for diagnosis because of their contribution to the outcome of the graft, regardless of presence of anti-HLA Abs. In postoperative RT patients, pathologic tumor size, margin status, extracapsular extension (ECE) and number of lymph node metastases, were also significantly predictive.

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Endovascular management of AEF can achieve satisfactory short and midterm results, better than those historically reported for open surgery, despite the high rate of recurrent bleeding and sepsis. Use of computer-assisted group study as a method to teach history of public health. Polarographic study on salivary proteins of the parotid gland in alveolar pyorrhea

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Employing a novel statistical method for the study of the health effects of chemical mixtures, we found evidence of neurotoxicity of the mixture, as well as potential synergism between arsenic and manganese. FG asymmetries were manipulated through familiarity of alcohol-IAT target categories and were assessed with visual search tasks.

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Functional properties of some varieties of African yam bean (Sphenostylis stenocarpa) flour--III. Predictors of depressive symptoms in older rural couples: the impact of work, stress and health. Together, these results indicate that Plin mediates hormone-stimulated lipolysis via direct and indirect mechanisms.

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Complete clearance of the avirulent strain ATCC 33707 occurred by day 14, while that of virulent ATCC 33704 and 33705 strains occurred by day 30. Selective inhibitors of cyclooxygenases-1 and -2 (SC-560 and NS-398) were used to investigate the relative contribution of each enzyme. Thio arsenosugars identified as natural constituents of mussels by liquid chromatography-mass spectrometry.

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Phosphorylation of the regulatory domain of dimeric DesR promotes, in a cooperative fashion, the hierarchical occupation of two adjacent, non-identical, DesR-P DNA binding sites, so that there is a shift in the equilibrium toward the tetrameric active form of the response regulator. The development of international emergency medicine: a role for U.S. Chronic infection by hepatitis C virus is an important public health issue.

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The three peaks present in the oligomer spectrum can already be obtained taking only one effective vibrational mode of the PTCDA molecule into account. Forty-two patients were enrolled in a randomized, double-blind, placebo-controlled parallel-subjects trial with a follow-up crossover trial. Modeling the controllable pH-responsive swelling and pore size of networked alginate based biomaterials. The objective of this study was to review available information on the chemistry, mechanism of action, in vitro auram aspect items for sale activity, resistance mechanisms, pharmacokinetics, tolerability and efficacy of minocycline against MRSA and A. It can lead to better outcomes when combined with medication compared to medication alone.

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The role of parvalbumin and calbindin D28k in experimental scrapie. The minor differences in OTU ranges of the primers did not greatly affect augmentin bloody diarrhea the observed community composition.

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Simulations show that passive articulation in micro air sievert india nerul india vehicles can increase their robustness to gusts within a range of joint compliance. The uptake/binding of CAN-296 to intact cells and to the cell-wall fraction of C. These results suggest that the ATBE is a cell-cycle-dependent process which requires actively dividing cells as receiving bystander cells.

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Therefore, risk factor identification and improvement of safety strategies for intracameral cefuroxime dosage vascular management are important. Despite significant differences in their peptide/protein profiles as determined using SDS-PAGE, HPLC, and mass spectrometry, all of the theraphosid venoms exhibited remarkably similar LD50 values of 46-126 microg/g for crickets and 0.5-4.0 microg/g for mealworms. Its status as a MAP is indicated by the observations that (i) it co-assembles efficiently with microtubules in vitro, (ii) it is localized on microtubules in brain sections by immunogold staining with monoclonal antibody against MAP5 and (iii) immunoaffinity purified MAP5 stimulates tubulin polymerization. Electroretinography in the differential diagnosis of visual loss in children. Another three patients with non-herpetic, non-paraneoplastic acute limbic encephalitis were presented.

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Monoclonal anti-leukemia inhibitory factor antibody inhibits blastocyst implantation in the rhesus monkey. Evidence for a local endothelin-angiotensin-atrial natriuretic peptide systemin bovine mature follicles in vitro: effects on steroid hormones and prostaglandin secretion. indica-colonized roots showed no induction of defence-related genes, while other genes showed a differential regulation pattern indicating a faster P. Analysis was performed on 61 women with chemotherapy-responsive metastatic breast cancer receiving 96-h infusional cyclophosphamide as part of a triple sequential high-dose regimen to assess association between presence of peritransplant congestive heart failure (CHF) and the following pretreatment characteristics: presence of electrocardiogram (EKG) abnormalities, age, hypertension, prior cardiac history, smoking, diabetes mellitus, prior use of anthracyclines, and left-sided chest irradiation. Along the axis, 1 week-old lenses showed a mitochondria amfebutamone hcl msds free zone (MFZ) starting 177 microm below the lens surface, whereas in 22 month-old lenses the MFZ started only 29 microm below the surface.

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In April 2007, there existed a repertory of 286 trials concerned with acute ischemic stroke on the Stroke Trials Registry (http://www.strokecenter.org/trials/), of which 209 trials were considered as complete (with no evidence of patient benefit unless one allina procap capsules dolce considers the much hard fought for and modest results of the tPA studies). Comparative measurements of piezoelectric coefficient of PZT films by Berlincourt, interferometer, and vibrometer methods.

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The purpose of lambipol dosage of amoxicillin this study was to investigate the effectiveness of prostaglandin E2 vaginal gel as used in practice, rather than its efficacy as assessed in randomised, controlled, clinical trials. The cholinergic nerve fibers enter the gland, where they are located both in the perivascular spaces and between the pinealocytes.