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Scleromyxedema is an unusual skin disease characterized by mucinous infiltration of the skin. RecBCD enzyme switches lead motor subunits in response to chi recognition.

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We describe the invasive and noninvasive diagnosis and treatment of non-palpable breast tumors. Comparison of suxamethonium and priming with atracurium for rapid sequence orotracheal intubation in a Nigerian adult population.

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Upper gastrointestinal endoscopic examination showed type 2 esophageal cancer in the lower thoracic area and type 3 gastric cancer in the upper body. Due to their low homology and relatedness to other known proteins, HPs may serve as potential, new drug targets. The current study elucidated for the first time that anti-schistosomal mechanisms of artesunate is mediated via reduction in expression of schistosome TGR and CcP. The effect of aggregated gamma-globulins on immune cytolysis: the role of complement.

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The Cayo Santiago colony opened new aspects of biomedical research and stimulated the general use of nonhuman primates in behavioral as well as physiological investigations. Ten studies provided detailed information on patterns of long-term use, many suggesting that the female condom reaches women less likely to use other dual protection methods. pombe can utilize phytic acid as a source of inositol under very specific conditions.

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Methadone, a long-acting mu-opioid agonist, is an effective treatment for heroin addiction. Phase shifts were different for each muscle, thereby altering their mechanical contribution to the pedaling action.

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Doxycycline-dependent switching can be tracked via fluorescent markers coupled to constitutive and tetracycline-regulated GOIs. Our model reproduces the overall shape of the measured autocorrelation traces and predicts that the short pulses are accompanied by substantial wings as a result of strong spatial hole burning. A further late-eluting compound was isolated as its acetate from the same fraction as the lolicines. We examined single-attribute and overall utilities in relation to weight status and BMI.

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The time between the sting and admission to the health center was less than three hours in both areas. Mutations of c-kit gene in bilateral testicular germ cell tumours in Japan. A significant similarity between the metalloprotease domain of the lethal factor and of that of the clostridial neurotoxins has been noted and is discussed.

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Are FDA and CE sacrificing safety for a faster commercialization of xenogeneic tissue devices? The purpose of this study was to describe the laparoscopic management of colorectal endometriosis at a tertiary referral center. On feeding, glucose influx triggers gene expression changes in hepatocytes to suppress endogenous glucose production and convert excess glucose into glycogen or fatty acids to be stored in adipose tissue. In the April 1999 issue of this journal, the author presented current research and discussed how environmental factors can be manipulated to prevent pressure ulcers in home care patients. The aetiology of many genital infections is still unknown or rather, an aetiological relationship between a given agent and a clinical manifestation is in some infections still debated.

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Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow. These changes were reduced by levcromakalim to the level during underperfusion with NE without glyburide.

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Staining for different subsets of DCs was performed using specific monoclonal antibodies. With regard to the Hedgehog (Hh) pathway, forward as well as reverse genetic approaches in this organism have not only validated the roles of evolutionarily conserved players of the signaling cascade, but have also contributed to the isolation of several novel components that had remained unidentified through screens in other animal models. Although clinical performance has been the focus of most evaluations of performance measurement to date, both patient care and provider satisfaction may improve more rapidly if all three categories of effects are considered when designing and evaluating performance measurement systems. Using this assay, KLK15 was detected in prostate, colon, and thyroid tissues, as well as in breast milk and seminal plasma. From July 1996 to October 2004, a total of 30,268 patients underwent heart surgery at Fuwai Hospital in Beijing.

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Cell migration from cerebellar and sciatic nerve explants is inhibited by anti-HSP90alpha and anti-HSP90beta antibodies, similarly to the inhibition observed with monoclonal antibody 4C5. Transmissible spongiform encephalopathy diseases are untreatable, uniformly fatal degenerative syndromes of the central nervous system that can be transmitted both within as well as between species.

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The clinical utility of patient-measured blood pressure at home in the management of hypertension. It thus appears that this antigen displays some crossreactivity between serotypes, and may be less exposed in bacterins than in live cells. How a pool of undifferentiated neural progenitor cells is maintained in the developing nervous system is an issue that remains unresolved. The expression of IL-17 and related cytokines, such as IL-22, was demonstrated in acute eczematous lesions independent of their pathogenesis.

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Treatment of osteonecrosis of the femoral head by free vascularized fibular grafting: an analysis of surgical outcome and patient health status. Delayed pneumomediastinum and pneumopericardium following slight laryngeal traumatism. Rehospitalization was more common for the bipolar than unipolar patients at the 4.5- and 7.5-year assessments. We used population data, estimates of chronic disease prevalence, and rates of medication adherence from the literature to estimate cost savings that would result from screening individuals aged 40 years and older who have seen a dentist but not a physician in the last 12 months.

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Our results showed that the use of Caucasian prediction equations, or a fixed percentage of their predicted values, resulted in misinterpretation of spirometry data in a significant proportion of patients. The present review summarizes recent evidence from studies with rodents and pigs supporting the hypothesis that activation of PPARalpha is responsible for the alterations in carnitine homeostasis previously observed. Modification of an in situ renaturation method for analysis of protein kinase activity with multiple substrates. Childhood psoriasis is more extensive and severe compared with that of adults.

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The effect of incubation of rectal biopsies on measures of proliferation using proliferating cell nuclear antigen in comparison with 5-bromo-2-deoxyuridine. Dating of black gel pen ink using the dissolution-diffusion method. Among the 80 pig vertebrae (90- and 140-day-old) tested in this study, the average screw pullout forces ranged between 419.9N and 1341.2N. Streptococcus pneumoniae carriage, specifically of vaccine-type strains, is negatively associated with S aureus carriage in children. To further understand the interactions of AuNPs with these surfaces, atomic force microscopy (AFM) force measurements were performed using citrate-modified Au-coated AFM tips and the same alkanethiol-modified Au substrates in aqueous solution at the same potential bias as for the AuNP collision experiments.

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Depression is a commonly associated psychological disorder in diabetic children, and should be addressed along with medical and dietary management. The finding is important because these are the only macrofossils found in Barra Honda Formation. Since epithelial cells provide a physical barrier against pathogenic microbes, we investigated their susceptibility to infection by H2O2-producing streptococci in this study. Integrity tests have become a prominent predictor within the selection literature over the past few decades. Gross demonstration of the mammalian atrioventricular bundle by a periodic acid-Schiff procedure.

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It is conceivable that suppressor cells that are present in vivo cannot act on mature effector cells generated in vitro. However, for the subset of patients with very-early onset IBD, several causal mutations have been found. Most cases were reported within hours with patients being asymptomatic or with relatively few complaints.

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The bone marrow microenvironment is known to provide a survival advantage to residual acute myeloid leukemia cells, possibly contributing to disease recurrence. The release of two prolactins, PRL(188) and PRL(177), which act in freshwater osmoregulation in teleost fish, rises in vitro within 5 min after extracellular osmolality falls. Such critical distance and the subsequent evolution of the split pulses are shown to depend on the source parameters and on the properties of the medium in which the pulse travels. Urinary pathology still arouses interest today most especially among those women who are entering old age and especially in relation to the fact that in this age static pelvic changes and trophism of the uro-genital organs occur with greatest frequency.

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The purpose was to examine the effect of a gait-retraining program on medial tibial stress syndrome incidence during a 26-wk basic military training regimen. Minimally invasive surgery has been developed to reduce incision length, muscle damage, and rehabilitation time.

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Cardiac and renal effects of standard versus rigorous blood pressure control in autosomal-dominant polycystic kidney disease: results of a seven-year prospective randomized study. In the general population of an area with high gastric cancer rate, H. To identify new SCA14 families and to describe the associated phenotype.

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Repair of such complex incisional hernias remains challenging, and further randomized controlled trials are required to elucidate the optimal method of closure and mesh type. A review on calcium phosphate coatings produced using a sputtering process--an alternative to plasma spraying. These results indicate that carbonic anhydrase might play a role in mercury toxicity. MEN1 mutations are mainly represented by nonsense, deletions/insertions, splice site or missense mutations that can be detected by direct sequencing of genomic DNA. Distributive shock is defined as circulatory insufficiency induced by excessive dilatation of the peripheral vasculature or maldistribution of cardiac output.

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Randomised controlled trial comparing efficacy of same day administration of mifepristone and misoprostol for termination of pregnancy with the standard 36- to 48-hour protocol. The International Society of Hypertension and the World Health Organisation have recently published new guidelines for the management of hypertension. Since December 1994, the Tropical Public Health Unit (TPHU) has maintained a register of all imported cases of dengue into NQ.

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A major challenge to breast cancer research is the identification of alterations in the architecture and composition of the breast that are associated with breast cancer progression. We reviewed studies on the predictive value of visual evoked potentials (VEPs) in the newborn. Multicenter trial of motion analysis for injury risk prediction: lessons learned from prospective longitudinal large cohort combined biomechanical - epidemiological studies.

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Cannabinoids are known to interact with CB1 and CB2 receptors expressed in the nervous and immune system, respectively, and mediate a wide range of effects, including anti-inflammatory properties. It presents the rationale for this approach and describes the service and preliminary outcome data.

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Proportional hazards regression models were used to analyse the risk of all-cause and diagnosis-specific disability pension with six exposure groups, established by mobility and weight status (BMI) obtained through self-reports. According to the Levine-Edwards classification, 25 cases were rated as type II, 15 cases as type II A, and 2 cases as type III. Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the National Veterans Affairs Surgical Risk Study. Quantitative levels of harmful oral microbes present following complex surgical excisions of head and neck cancer are important since wounds are often contaminated through direct connection to the oral cavity and its flora.

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The author proposes a review about pulmonary disorders and gastroesophageal reflux. Trace-metal contamination of the African giant land snail Archachatina marginata from Southern Nigeria. The utility of the Theory of Planned Behaviour (TPB) has not been previously investigated in explaining this variance in community nursing. Through both techniques, mussels collected from the port of Thessaloniki displayed concentrations of metals higher than those recorded in mussels from Halastra and Olympiada.

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Current Cancer Immunotherapy Using Activated Lymphocytes - Do Lymphocytes Actually Recognize Cancer Cells ? The anaesthetic practitioner filled in an assessment form giving a score on nine criteria for each blade used. CSDH is a documented complication of intracranial arachnoid cyst, the incidence of which is increased in patients with ADPKD.

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Dental unit water systems (DUWS) are used in dental practices to provide water to irrigate the oral cavity. THE EVOLUTION OF A CAROTID SINUS REFLEX AND THE ORIGIN OF VAGAL TONE. For the past few years, the cardiovascular stenting experienced an impressive growth. The uptake of cadmium as 109Cd-cysteine was greater and that of 109Cd-metallothionein lower compared with that of the other substances. DFT study on the reactivity of iron porphyrins tuned by ring substitution.

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Indoor air pollution (IAP) from combustion of biomass fuels represents a global health problem, estimated to cause 1.6 million premature deaths annually. Vasomotor adjustments in the microcirculation during changes in blood distribution. Comparison of the levels of copper, zinc and iron in cervical mucus and in blood serum of women of childbearing age.

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The adrenal mass was a cortical adenoma with solid and nested patterns, with discrete zones consisting of erythroid, myeloid and megakaryocytic cells intermixed with mature adipocytes. The change type was also manipulated so that accurate detection depended on color or the binding of color and location. Effects of glycation on the ability of the antibodies to bind antigens are contradictory. Wild-type but not G546R mutant FANCG physically interacts with the mitochondrial peroxidase peroxiredoxin-3 (PRDX3). Real-time probing of membrane transport in living microbial cells using single nanoparticle optics and living cell imaging.

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In the current study, the monomeric size of AlgZ was estimated to be between 6 kDa and 15 kDa by electroelution of a protein preparation from an SDS-PAGE gel and analysis of the fractions via protein staining and electrophoretic mobility shift assays. Thus, the aim of our study was to assess daily food consumption, habits, symptoms, sleep, and perceived experience of patients undergoing pH testing as compared to an off test (normal) day.

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In Experiment 1, all the control and saline-infused rats exhibited the expected rise of plasma LH two days after estrogen injection while the POA/KA-infusion abolished the positive feedback effect of EB on LH release. Wrist activities were monitored by Actigraph for 10 or 14 consecutive days.

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All randomised controlled trials (RCTs) comparing intramuscular BtA injections into any muscle group of the upper limb with placebo, no treatment or other interventions. Due to uncertainties in antiproton dosimetry we defined a new term, called the biologically effective dose ratio (BEDR), which compares the response in a minimally spread out Bragg peak (SOBP) to that in the plateau as a function of particle fluence.

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Successive work of others suggests inactivity of Bak always accompanies the development of tumor cells. In the last week of gestation a rapid increase of magnesium concentrations both in maternal (0.83 mmol/l) and fetal (2.84 mmol/l) serum was determined. Obstruction of the small bowel due to carcinoma of the ascending colon.

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Pediatric emergency physicians completed standardized data collection forms on eligible patients. Current process-focused theories bearing on personality invoke a view of the individual in ongoing action and interaction with the environment, reflecting a flow of experience rather than a static depiction. Body temperature is easily measured and manipulated in the ICU, and interventional trials defining the most appropriate temperature targets in ICU patients with infections are urgently needed. The task activation level, defined as the percentage MR signal increase for each task relative to REST, and the differential activation, defined as the percentage MR signal increase for RAND and SELF relative to FIX, were calculated in each area. During the hot plate test, the WKY and LE showed a lower thermal threshold compared to the BN and FH.

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The 7-carbamate groups of geldanamycin and its 17-(2-dimethylaminoethyl)amino-17-demethoxy derivative (17-DMAG) bind the N-terminal domain of Hsp90 by establishing a network of hydrogen bonds which involve four buried water molecules. This effect was prevented by pretreatment with the dopamine antagonists haloperidol and metoclopramide, but not with the alpha-adrenergic antagonist phentolamine. We aimed to evaluate whether a similar strategy could be used to control cardiac-tissue excitability. As a pilot study for a national campaign to promote the use of screening mammography, the Virginia Division of the American Cancer Society conducted a breast cancer awareness project with mammography screening. These studies link HTLV-1 infection with changes of cellular cyclin gene expression, hence providing clues to development of T-cell leukemia.

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