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The metabolic fate of 14C or 35S labelled tiadenol in rabbit after i.v. Cholinergic-like effects of the new histamine H2-receptor antagonist ranitidine. A damage of the kidney, particularly of proximal tubular cells, can be indicated by an increased concentration of definite enzymes in urine. An adequate animal model of a psychiatric condition must fulfill three core criteria: share pathophysiological characteristics of the human condition (face validity), have similar behavioral manifestations as the human disease (construct validity), and improve with medications that improve the symptoms seen in afflicted humans (predictive validity).

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The aim was to follow-up gonadal functions in long-term survivors of acute myeloid leukemias (AML) after intensive chemotherapy based on high-doses of cytosine arabinoside (Ara-C) and anthracyclines in the study UHKT-911. We found that enzymatic removal of terminal galactose residues, which exposes N-acetylglucosamine residues, increases uptake of soluble IgG mediated by mannose receptor on macrophages and dendritic cells. Dystroglycan, a central component of the DGC, serves as a laminin receptor via its extracellular alpha subunit, and interacts with dystrophin (and thus the actin cytoskeleton) through its integral membrane beta subunit.

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In this article, we evaluate the most common long-term complications of the most commonly performed bariatric interventions. The analysis of other compounds of exhaled air, particularly those of exhaled breath condensate (EBC), offers fascinating perspectives, owing to the scope of markers that might be measured, and could enable the assessment of multivariate profiles that are useful for diagnosis and therapy control. How stimulus contrast affects visual perception and visual memory.

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A massive cardiopulmonary resuscitation (CPR) training programme is continued in most hospitals to make hospital personnel ready to take action in cases of cardiac arrest. The control of the secretion of these proteases and the activation of proenzymes by other proteases such as plasmin, as well as the balance between MMP secretion and the secretion of their natural inhibitors (TIMPs), have an important relevance in the pathogenesis of multiple sclerosis (MS). Water is the major solvent component in living cells, and the properties of water in the highly crowded media inside cells differ from that in buffered solution. p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel.

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Optimization strategies were based on the previous screening of the most important instrumental factors like number of cumulated scans, nominal resolution, mirror velocity and zero filling factor, based on a two-level full factorial design and on the search for the optimum conditions using central composite designs. Because disease aggressiveness is correlated with CD26 expression in several T-cell malignancies, we decided to investigate the invasiveness of cells expressing different levels of CD26.

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Studies that focus on a single structure, across a larger number of taxa, are more insightful and present specific questions that can contribute to broader issues, thus providing a better understanding of the morphology and evolution of insects. It aims to provide FRACGP candidates with a practical approach to exam preparation. PE exposure led to negative effects on diatom growth kinetics independently of in-field biofilm exposure history. Experimental transmission of toxoplasmosis by tick Ornithodorus moubata During the first urine examination large numbers of erythrocytes and leucocytes were seen.

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Unilateral knee joint endoprosthesis for treatment of varus or valgus gonarthrosis (indications--technic--late results Taken together, these results suggest that glucocorticoid treatment directly induces transcription of the p57Kip2 gene and that the p57Kip2 protein is involved in the glucocorticoid-induced antiproliferative effect. The assessment of airway inflammation and bronchodilator responses can help the selection of specific therapies and the prediction of clinical outcomes for COPD patients.

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Biochemical analysis using denaturing gel electrophoresis on dissolved crystals informs on the content of the crystal. Prepared compounds were found to exhibit significant antinociceptive activities and could be used as potential analgesic agents. The effects of DHA and EPA were associated with a significant reduction in the amount of FITC-PrP82-146 that accumulated within synapses.

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The patients who were found to have GER in ambulatory esophageal pH monitoring were randomized to receive either omeprazole, 40 mg qd, or placebo for 8 weeks. Model predictions imply that the decline in bioreactor performance observed over extended operation was caused by a decline in the active biomass fraction and a decrease in the biofilm specific surface area. The lateral areas of the plate tended to form non-neural tissues more than the medial areas.

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Spinal immobilisation for unconscious patients with multiple injuries. The study demonstrates that South Africa has been experiencing a high epidemic of HIV, which demands urgent attention and care through the provision of simple, cost-effective and voluntary counseling and testing services in order to help prevent the spread of the disease. Main group bismuth(III), gallium(III) and diorganotin(IV) complexes derived from bis(2-acetylpyrazine)thiocarbonohydrazone: synthesis, crystal structures and biological evaluation.

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These data reveal the complex roles of DHX30 in HIV-1 replication and implicate an inhibitory activity of DHX30 in HIV-1 RNA packaging. The spectrum of phytoestrogens in nature: our knowledge is expanding. It is well recognized that maintenance of genome integrity relies on the accurate execution of the DNA replication process as well as on efficient DNA repair.

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Isolated nuclei from G2 phase cells contain an active phospholipase activity capable of generating DAG in vitro. In the prosencephalon, differences in spatial constraints may explain the variability in the orientation of cell clusters. Gastrectomy below the site of the ulcer in cases of ulcers situated high in the stomach Effect of carbendazim resistance on trichothecene production and aggressiveness of Fusarium graminearum.

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In vitro measurement of Michaelis-Menten kinetic constants revealed that the Asn152Ser mutation causes a selectivity switch for penicillin G versus cefoxitin. Whereas most glycocalyx research has traditionally focused on the microvasculature, more recent data have underscored the importance of the glycocalyx in protecting the macrovasculature against pro-atherogenic insults. Morbidity was comparable with 1 late Clavien IIIb complication in each subgroup (open, converted, and robotic group). Vasculitis supervened on a prior systemic sclerosis, and no causative disorder of hemophagocytosis could be found other than active vasculitis, suggesting that an occurrence of hemophagocytosis is associated with underlying vasculitis. Moreover, the procedure results in lower rates of infection, skin necrosis and breakage of the cutaneous bridges.

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GFE, genipin, and geniposide showed acute anti-inflammatory activities in carrageenan-induced rat paw edema. Effect of larval brain on the imaginal differentiation in the silkworm. An experimental model to perform dynamic studies of exocrine pancreatic secretion from mice has been developed. In the present experiments, we studied the effects of the CB1 antagonist AM-251, and the cannabinoid agonist WIN-55,212-2 in wild-type as well as in CB1 knockout mice. Registration is expected to be a collaborative process among companies, which will generate a dossier containing data on physicochemical characteristics, as well as toxicological and ecotoxicological properties.

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The subjects were 20 children (10 females, 10 males) with repaired CP and 16 control (i.e., unaffected) children (8 females, 8 males). Serum carnitine levels in chronic hepatitis C patients before and after lymphoblastoid interferon-alpha treatment. It is suggested that the somatic growth and the increase in excitability is regulated by the excitatory afferents. Cryopreserved-thawed embryos have a lower rate of pregnancy than fresh embryos, which might be due to hardening of the zona pellucida.

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Since the loss of cartilage-associated protein (CRTAP), which is required for post-translational prolyl 3-hydroxylation of collagen, causes severe osteoporosis in mice, we investigated whether CRTAP deficiency is associated with recessive osteogenesis imperfecta. This study was intended to investigate the effect of dexmedetomidine on oxidative stress response in pneumoperitoneum established in rats. A QSAR toxicity study of a series of alkaloids with the lycoctonine skeleton. Competitive Adsorption of Cd(II), Cr(VI), and Pb(II) onto Nanomaghemite: A Spectroscopic and Modeling Approach. Lower limb manual muscle testing in the early stages of Charcot-Marie-Tooth disease type 1A.

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Continuous cardiac output monitoring with pulse contour analysis: a comparison with lithium indicator dilution cardiac output measurement. Flow rates of 2 mL/sec, representative of flow through small diameter blood vessels, can be generated, resulting in a mean wall shear stress of approximately 6 dynes/cm(2) within the 3 mm ID constructs. The long arm of chromosome 6 is frequently rearranged in human cancer.

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Template convolution to enhance or detect structural features in macromolecular electron-density maps. Between December 1999 and September 2004 we endovascularly treated seven patients (6 men, 1 woman, mean age 41.7 years) for blunt aortic injury of the thoracic aorta. Alternatively, excess food intake may cause gastrointestinal (GI) symptoms in obese patients. Effects of barbiturate anesthesia on functional residual capacity and ribcage/diaphragm contributions to ventilation.

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The loading conditions studied included unilateral and bilateral loading of the prosthesis. Spodoptera litura multicapsid nucleopolyhedrovirus (SpltMNPV) ORF120 (designated as the bro-a gene) is a member of the unique multigene family called the baculovirus repeated ORFs (bro) family.

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In contrast, RPA inhibits Rad51 nucleoprotein complex formation by prior binding to single-stranded DNA (ssDNA), but Rad52 protein alleviates this inhibition. Detection of venous thrombosis in the human by means of radioiodinated antifibrin-fibrinogen antibody. In spreads of mesenteric adipose tissue, the technique makes it possible to distinguish between lipoprotein lipase activity at sites in the capillaries and lipolysis occurring in the adipocytes. Transabdominal removal of femoral and acetabular components of a severely protruded and infected hip arthroplasty with urinary tract complications

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Hydrosalpinx fluid negatively affects murine embryo development, but its presence in the uterine horn at ET did not affect implantation. Advances in whole-genome and whole-transcriptome amplification have permitted the sequencing of the minute amounts of DNA and RNA present in a single cell, offering a window into the extent and nature of genomic and transcriptomic heterogeneity which occurs in both normal development and disease. The assessment of patients with myelodysplastic syndromes (MDS) and the choice of therapies remain challenging. Non-parametric methods are proposed to calculate cumulative risks for cases without covariates.

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Obesity is a major public health concern in the United States and its prevalence is increasing. Alexithymia was correlated positively with depression, emotional exhaustion and depersonalization, and negatively with sense of family support and personal achievement. Xylanases of ruminal strains were widely studied, but few studies have focused on their diversity in rumen microenvironment.

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She had a 3-week history of headache, vomiting and a tendency to fall to the left side, and suddenly developed respiratory arrest followed by coma. Clinical trial evidence describing best practice is limited, but recent data supports the strategy of adding fenofibrate to a statin, and suggests specific benefits in dyslipidemic patients and in the improvement of diabetic retinopathy. The native-like interactions between SNase121 and SNase(111-143) fragments induce the recovery of their native-like structures and the ability to degrade DNA. The organic derivatives were potent inhibitors of the cathepsins and clear specificities were detected, which were parallel to their known substrate specificities. While oncogenic forms of Abl appear to be anti-apoptotic, the function of c-Abl remains elusive.

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In these 3 cases, patients with postsurgical spine pain responded positively to chiropractic care. Two types of end-to-end colorectal anastomosis using a circular stapler, circular stapled anastomosis(CSA) and double stapling anastomosis(DSA), have become the standard technique. Measurement of temporal stability in culture medium suggested that covalent bonding between alginate and AtCol might contribute to the structural stability of the alginate-modified AtCol gel. Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data.

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The short-term success rate following the bulbourethral sling procedure is high but persistent perineal discomfort is common. Ex situ population management in the absence of pedigree information. Finally, our results suggest that the conjugates bind directly to integrase within its complex with DNA at a site different from the viral DNA binding site. Our results demonstrate that mRNAs undergoing leaky scanning are a new class of endogenous NMD substrate, and suggest the existence of a novel cellular regulatory circuit. Merkel cell carcinoma (MCC) is an uncommon aggressive primary cutaneous carcinoma with neuroendocrine differentiation.

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Actual quantity of C1P in cells (6 pmols/10(6) cells) was much lower than previously reported. The focus of this article is on the recent progress in understanding the role of BETA2/NeuroD1 in the development of the nervous system. Transcriptional suppression of rat angiotensin AT1a receptor gene expression by interferon-gamma in vascular smooth muscle cells. Levels of blood lipids in children were influenced by age and sex, and correlated with indicators that reflect their body fat and nutritional status.

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It is now clear, however, that the brain is sensitive and responsive to diet composition. FSH receptors are addressed to the basolateral domain of cells through specific signaling mechanisms. An atypical form of parkinsonism has been described in patients with chronic liver disease, associated with increased T1 signal in the basal ganglia on magnetic resonance imaging. However, these procedures are associated with an increasing rate of several, sometimes severe intraoperative and postoperative complications.

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Clinical terminology servers are distinguished from more broadly based terminology servers intended for nomenclature development or mediation across classifications. Position error correction of large-aperture aspherical in-position measurement. Western blot results showed upregulation and activation in both caspase-3 and caspase-8 protein. High-dose statin pretreatment can reduce the rate of PMI, irrespective of either the clinical presentation or previous statin-treatment history.

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Although the possibility of stabilization of the ferroelectric phase due to the surface energy effect has been theoretically suggested, such a theoretical model has not been systematically compared with actual experimental results. We found that plasma total and active PAI-1 levels increased in a circadian manner in mice with streptozotocin (STZ)-induced diabetes.