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However, full doses of cisplatin cannot be delivered in patients with impaired renal function. Without global signal correction, the distributions of the correlation coefficients were positively biased. The formulation provides an alternative therapy for acute bacterial conjunctivitis that should improve patient compliance and satisfaction.

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Likewise, cancer incidence data from 1990 to 1993 were obtained for seven rural-poor counties in North Carolina from the North Carolina Central Cancer Registry. Alpha-tectorin is a noncollagenous component of the tectorial membrane which plays an essential role in auditory transduction. Nonaggressive boys had a prolactin response midway between those of the two aggressive subgroups, and their prolactin response did not vary as a function of parental aggression. Support for the involvement of cytokines in depression comes from studies showing their elevation in severe depressive illness and following stressor exposure, and that cytokine immunotherapy (e.g.

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The characteristics of both hemagglutinin inhibitors and growth inhibitory substances of influenza viruses found in animal specimens. Re: Magnetic resonance imaging in the diagnosis of seminal vesicle cysts and associated anomalies.

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The temperature dependence of these ratios was calibrated with corals collected at SST recording stations and by (18)O/(16)O thermometry. Their plasma membrane phospholipid/cholesterol profiles were compared with those observed in either control tissues or tissues obtained one to two hours post-renal damage (that is, prior to emergence of CR). Through spectroscopic quantitative analysis, Cd(II) in aqueous solution can be detected as low as 4.6 nM. Effect of hot climatic conditions in the city of Erevan and of mountain climatic factors on chronic dysentery in children

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arnottiana were investigated for their terpenoid compositions by means of GC and GC/MS analyses of their essential oils, as well as by one- and two-dimensional NMR studies of the isolates. Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode. Although many patients with positionally provoked vertigo have typical benign paroxysmal positional vertigo, physicians should be aware of nonbenign variants.

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The mTOR inhibitor rapamycin and its derivatives are cytotoxic to a number of cell lines. Clonal nature of fibroblast colonies formed by stromal bone marrow cells in culture Noradrenaline and adrenaline activated cytochrome c oxidase in liver, brain and kidney tissues.

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The data obtained from studying the transient processes in clinically healthy children of different age groups may be used as the reference criteria in clinical studies of vegetative disorders, for establishing scientifically-based age-differentiated regimens for children with regard to adaptive potentialities of the body, as well as for the development of age periodization. An intriguing feature of these mutants is that they have a competitive fitness advantage when grown in competition with the parent strains in stationary-phase cocultures which is independent of RpoS, the only locus known to be primarily associated with acquisition of a growth advantage phenotype in bacteria.

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Antibodies directed against mouse hepatitis virus (MHV) virions and against the putative RNA-dependent RNA polymerase (Pol) detected SARS-CoV nucleocapsid and nsp12 (Pol), respectively, in SARS-CoV-infected Vero cells. The unconditioned inhibition of feeding in a novel setting (hyponeophagia) was reduced by propranolol and another potentially centrally acting beta-adrenoceptor antagonist, pindolol but not by a peripherally acting one, atenolol. Experience with the quantitative presentation of case records (use of the Malamud-Sands scale) The assignment of healthier patients to trials comparing mini-laparotomy cholecystectomy and laparoscopic cholecystectomy limits the external validity of conclusions reached in such trials. On periarteritis nodosa cutanea or vasculitis nodularis of the legs of young women

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Initial PEG concentration (5-50 mM) and coupling time (0.5-24 h) were varied to attain different grafting densities, and different PEG interfaces so created were analyzed using XPS and AFM. Additionally, in the morphological study performed to analyse cortical thickness and the number of GFAP-, CaBP-, PV- and Fos-immunostained cells no differences were seen between the two groups studied. The synthesis of the L-serine ligands proved to be highly efficient and straightforward. Prevalence of Budd-Chiari Syndrome during Pregnancy or Puerperium: A Systematic Review and Meta-Analysis.

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These results suggest that hypothalamic cells can convey information independently of their mean firing rate. The symptoms subsided after 5 days and ENL lesions healed in 2 weeks. We also observed that in E5-expressing cells, treatment with PMA results in an increase in membrane-associated PKC activity, and a superactivation of the ERK1/2 MAP kinases. It became clear that the intrahepatic stones contained high levels of free bile acids and that bacterial infection, which deconjugates the glycine and taurine conjugations, is involved in the pathogenesis of gallstones. A simple noise generator for use in neurophysiological and behavioral research.

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Our results indicate that malaria transmission risk in Greece is potentially substantial. Experimental study of augmentation phalloplasty using tunica vaginalis grafts in bilateral albuginea of penile corpus Maybe the most important lesson from this overview is the notion that the anabolic-catabolic balance as such counts and not so much sufficient net anabolism or limited catabolism alone. Testing antisecretory drugs in Zollinger-Ellison syndrome: problems and limits in pharmacological studies.

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Down-regulation of PARP1 by miR-891b sensitizes human breast cancer cells to alkylating chemotherapeutic drugs. The dependence of the amide group flexibility on the environment polarity may have interesting consequences for peptide and protein folding studies. The prevalence of the ICAM-1/LFA-1 and VCAM-1/VLA-4 patterns of mononuclear blood cell/sinusoidal cell interactions could support the macrophage-induced or lymphocyte-induced type of liver injury. Transition metals in atmospheric liquid phases: sources, reactivity, and sensitive parameters. Twelve patients from six pedigrees were ascertained from pediatric and adult epilepsy centers, eleven of whom underwent epilepsy surgery.

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The biopolymer welan gum is synthesized by the fermentation process mainly by the Alcaligenes sp., and is composed of polymer of tetrasaccharide backbone chain containing l-mannose, l-rhamnose, d-glucose, and d-glucuronic acid. After initiation of the low iodine diet, both sexes showed similar decreases in serum T4 and similar increases of serum TSH and thyroid weight. Controversial studies have shown favorable effects of beta blockers on myocardial metabolism and energetics, the coronary microvasculature, collateral blood flow, the distribution of myocardial blood flow, oxygen-hemoglobin affinity and platelet function. The utility of the efficient plant extracts for vector control as an alternative to pyrethroids may thus be envisaged. Best-corrected visual acuity (BCVA), fundus examinations, Goldmann perimetry, color vision tests, and full-field electroretinograms (ERGs) were evaluated.

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The teams reviewed their specific utilization and cost data, and the physicians led consensus-building conversations over a series of team meetings to agree to standard supply utilization. Removal of the sulphate groups via sulfatase treatment led to a dramatic decrease in Etx-induced cytotoxicity, but not in proEtx-GFP binding to MDCK cells or a significant shift in oligomer formation, pointing to a role of sulfatide in pore formation in rafts but not in toxin binding to the target cell membrane.

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Identification of the structural properties of the glycocalyx has led investigators to examine its various functions and it has since been recognized as playing a role in many physiological processes, one of which is the regulation of fluid and protein exchange across the capillary wall. Rates of lipid oxidation do not suppress effectively in response to insulin, but neither do rates of lipid oxidation effectively increase during the transition to fasting conditions. Controls introduced in Experiment 2 did not change this pattern.

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Expression of toll-like receptor-4 on intrahepatic mononuclear cells isolated from AdGM-primed mice was up-regulated. Effect of active smoking on the human bronchial epithelium transcriptome.

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Mechanisms involving intracellular signaling pathways that regulate synaptic strength are described, and the specific roles of calcium, protein kinases, protein phosphatases, and retrograde messengers are emphasized. Treatment directed at the underlying cause relieves symptoms and improves quality of life. A novel mouse protein differentially regulated by androgens in the submandibular and lacrimal glands.

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Unfortunately, it is still challenging to make uniform graphene-semiconductor composite films with controllable film thickness and architecture, which are of paramount importance to meet the application requirements. Lactobacilli expressing the scFv fragment fused to an E-tag were visualized by scanning electron microscopy (SEM) using beads coated with a monoclonal anti-E-tag antibody, and they bound directly to beads coated with SAI/II.

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Numerous articles indicate that vitamin D and calcium deficiencies result in bone loss and increased inflammation, which are well recognized symptoms of periodontal disease. The ability of activation by MMP-triggered dePEGylation and charge shift is demonstrated to substantially increase the uptake and the silencing efficiency of the LNPs. 116 patients referred for evaluation of moderate to severe symptoms of OSA in which both home oximetry and polysomnography (PSG) were performed.

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Population-based cohort from the Pittsburgh Center of the Study of Osteoporotic Fractures (SOF). Basic levels of coronary, systemic circulations and oxygen metabolism in dogs under anesthesia Cardioversion for atrial fibrillation: treatment options and advances. Revealed by acute hemolysis, this complication needed an emergency surgical operation. Both anti-mdr-1 ribozyme RZ196 and RZ179 can stably reverse MDR phenotype of breast carcinoma cells in vitro.

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When combined with polygodial, nagilactone E, and n-dodecanol, anethole has been shown to possess significant synergistic antifungal activity against a budding yeast, Saccharomyces cerevisiae, and a human opportunistic pathogenic yeast, Candida albicans. Two matched control groups of primiparas, one of whom had cesarean section and the other a normal vaginal delivery. We show that three and one binding site within the hTERT and mtert promoters, respectively, that express a unique conserved region are responsible for the transcriptional activation of TERT. A possible explanation to these patterns is extensive hybridization and gene flow within Heliosperma, which together with concerted evolution may have eradicated the ancient divergence suggested by the rps16 data.

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Pharmacological experiments indicated that epidermal cell death was dependent on signaling through G proteins. The potent induction of angiogenesis by Fkn can be used as a therapeutic strategy for alleviating peripheral ischaemia. Exudative AMD is currently most often treated monthly with anti-VEGF intravitreal injections. To alter this trend, strategies and programs for weight maintenance as well as weight reduction must become a higher public health priority.

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The following factors were evaluated for an association with outcome: dog age and sex, clinical signs, anemia, thrombocytopenia, neutrophilia, tumor stage at diagnosis, achievement of complete excision, intramuscular involvement, presence of gross disease, tumor recurrence, and treatment. Comparative study of the analgesic activity of glafenine and a paracetamol-codeine combination in post-operative dental pain

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Unexpectedly, FLN was found in the apicoplast, an essential chloroplast-like organelle. We found 15 randomised-controlled trials of pedestrian safety education programmes, conducted between 1976 and 1997.

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Both methods of flicker perimetry testing provide acceptable test-retest reliability, and both can distinguish normal subjects from glaucoma patients. Apatite can mediate gene transfer into cells by serving as a safe and biocompatible immobilization matrix for DNA and transfection reagents. As described by Eugene Wolf, arthroscopic shoulder stabilization using the Mitek (Mitek Surgical Products, Ethicon, Edinburgh, U.K.) anchors requires two anterior portals and intra-articular knot tying.

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Dose-response relationships in a cytochemical section bioassay for thyroid stimulators. In this article, we demonstrate experimentally how this protective defense system employed by the brown lacewing (Micromus tasmaniae) aids in resisting contamination from water and how the micro- and nanostructures found on these hairs are responsible for quickly shedding water from the wing which demonstrates an active liquid-repelling surface.

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The objective of this study was to examine the effects of short (2 h) and prolonged (18 h) inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate (PA) induced insulin resistance in L6 myotubes. To determine the window of detection of zolpidem in both urine and hair, three volunteers received a 10 mg dose. The patients did not show any differences in mitochondrial function such as phosphorylation potential and the ratio of the rate of ATP synthesis. Moreover, studies of ventilator-induced lung injury revealed induction of the ADORA2B during ALI in vivo that was abolished following HIF inhibition or genetic deletion of Hif1a. Dracorhodin perchlorate induces apoptosis in primary fibroblasts from human skin hypertrophic scars via participation of caspase-3.

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Sixty-two women affected by locally advanced squamous cervical carcinoma treated with TP (paclitaxel 175 mg/m2 over a 3 h infusion plus cisplatin 75 mg/m2) or TIP (TP plus ifosphamide 5 mg/m2) were examined and scored according to the Total Neuropathy Score (TNS), before and during chemotherapy. Her seizures were a probable adverse drug reaction based on the Naranjo scale. Regional sex differences in volume and tissue density include the amygdala, hippocampus and insula, areas known to be implicated in sex-biased neuropsychiatric conditions.

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Researches conducted on dogs, used as sentinels for community exposure to environmental carcinogens, can be useful to detect excess risks in the incidence of malignant tumours in the human population. A protocol for the in vitro selection of specific oligonucleotide probes for high-resolution DNA typing. Duration of Hospitalization in Association with Type of Inhalation Therapy Used in the Management of Children with Nonsevere, Acute Bronchiolitis. The levels of ANP mRNA expression in the heart remained unchanged, but in the kidney ANP mRNA levels were increased in the 7-day water-deprived mice, and were significantly decreased in the 14-day water-deprived mice.

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After VBG, PYY concentration gradually rises to the control levels. Laboratory diagnostic and prognostic factors: Multiple myeloma in Morocco

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The European Centre for Disease Prevention and Control sought to determine the frequency of evaluations amongst European national public health programmes by using national hand hygiene campaigns as an example of intervention. Additives that are good hydrogen-bond acceptors increase the efficiency of gold-catalyzed reactions in those instances where protodeauration is the rate-determining step. Frail and prefrail older adults present lower eRMR than nonfrail adults. In contrast, in u-PA-deficient mice, the decrease in damage size and the accumulation of macrophages were impaired.

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Qualitative and quantitative detection of contaminating malignant cells in stem cell apheresis products intended for supportive therapy after high-dose chemotherapy of sensitive solid tumors is a demanding task for the laboratory. Immunophenotypic comparison of blood and lymph node from dogs with lymphoma.