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We found that although H-Ras modified with FPP analogues p-NO2-AGPP, p-CN-AGPP, and Isox-GPP was an efficient substrate for C-terminal postprenylation processing by Rce1 and Icmt, co-injection of H-Ras with analogues p-NO2-AGPP, p-CN-AGPP, or Isox-GPP could not activate MAPK. The diode laser with its wavelength in the near infrared (810 nm) makes lens sparing transscleral retinal coagulation possible. This article investigates the empirical basis for often-repeated arguments that gender differences in entrance into STEM majors are largely explained by disparities in prior achievement.

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DOSAGE PROBLEMS IN THE TREATMENT OF UTERINE CARCINOMA WITH COBALT 60 PEARLS Adhesions form between damaged mesothelial surfaces and can cause recurrent small bowel obstruction. Abortifacient provision is common at pharmacies but knowledge about medications is low among pharmacy staff. To provide results of water calorimetry and ion chamber measurements in high-energy electron beams carried out at the National Research Council Canada (NRC).

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After 13 years, the retired men still had twice the rate of the referents. Here we present a model of bacterial evolution in overlapping habitat space. Neurological diseases caused by encephalitic flaviviruses are severe and associated with high levels of mortality.

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Additionally, endothelial dependent and independent vascular sensitivity to acetylcholine and sodium nitroprusside were evaluated. At a concentration of 1 microM, staurosporine delayed functional recovery assessed by measuring synaptic field potentials across the lesion, without altering synaptic transmission on nonlesioned cultures. Tissue specimens were obtained from patients undergoing pterygium excision. Otitis media, tympanostomy tube placement, and use of antibiotics. The optimized operator is suitable for collapsing real source-reconstructed M/EEG data into any cortical parcellation.

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Using low-E resonators to reduce RF heating in biological samples for static solid-state NMR up to 900 MHz. The SPG8-linked family had a significantly older mean age at onset of symptoms and had significantly more wheelchair-using patients than the four linkage-excluded families. The enzyme also lysed other beta-haemolytic streptococci, including groups A, C, E and G streptococci, but not common oral streptococci, including Streptococcus mutans.

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Using a variety of approaches such as microstimulation of the spinal cord, NMDA iontophoresis, and an examination of natural behaviors in intact and deafferented animals we have provided evidence for a modular organization of the spinal cord. Prevalence and predictors of unintended pregnancy among women: an analysis of the Canadian Maternity Experiences Survey. Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3. The non-phospholipid formulation of stratum corneum liposomes showed the highest encapsulation efficiency after preparation among nine liposomal formulations. Influenza matrix protein-2 (M2) is highly conserved across influenza subtypes and a promising candidate for a broadly protective influenza vaccine.

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It consists of 13 subunits (eIF3a to -m), among which eIF3b serves as a major scaffolding protein. The diagnosis of ARVC/D was established according to the recently revised Task Force Criteria. The authors have identified 5 groups of patients with essential hypertension in the recovery period of ischemic stroke. Postoperative complications after recrossectomy of the saphenofemoral junction

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High dose barbiturates can be used only in patients in whom other treatment modalities failed to decrease the raised intracranial pressure. A key goal of systems biology is to elucidate molecular mechanisms associated with physiologic and pathologic phenotypes based on the systematic and genome-wide understanding of cell context-specific molecular interaction models. In the first stage, division of the inferior vena cava was performed.

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Study of decreased oral intake in patients receiving neoadjuvant chemotherapy for esophageal cancer Estimates of the impact of long-term HRT on risk of coronary events, hip fractures, and breast cancer were summarized as relative (proportional) decreases or increases in risk, or as NNT. Genomic features in the breakpoint regions between syntenic blocks. Air samples were collected and analyzed in accordance with US Environmental Protection Agency-approved methods.

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Renal function was not impaired by treatment with 5-aminosalicylic acid in rats and man. In in vitro kidney proximal tubular cell lines, PARP inhibition by postconditioning also diminished HMGB1 release from cells. Analysis of Critical Dimensions for Nanowire Core-Multishell Heterostructures. Multivariate linear regression was performed to examine whether stress levels were related to coping and resilience.

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We used an intracellular processing system to monitor the solubility of these passenger proteins after they were cleaved from MBP and NusA by tobacco etch virus protease. Recurrent massive subcutaneous hemorrhage in neurofibromatosis type 1: a case report. What is the effect of anti-resorptive drugs (ARDs) on the development of medication-related osteonecrosis of the jaw (MRONJ) in osteoporosis patients: A systematic review.

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Subcutaneous ivermectin use in the treatment of severe Strongyloides stercoralis infection: two case reports and a discussion of the literature. While some sectors in medicine have been quick to adapt modern developments, drug treatment has consistently lagged behind because of traditional, but dated, prescribing habits or persistent trade profits. We systematically reviewed recent literature to determine whether caseload and surgical speciality are associated with short-term outcome following colorectal cancer surgery. 435 newborns delivered below 28 weeks of pregnancy, 28-32 weeks of pregnancy and above 32 weeks of pregnancy were studied. Hip joint movements were provoked by a lift jack, elevating the feet to the volunteers, which sat on a bicycle chair.

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Myelination was enhanced and ventriculomegaly reduced in hypoxia-exposed neonatal pups treated with caffeine from P3 to P12. The conventional double-phase 99mTc-MIBI parathyroid scintigraphy was negative. Disability arising from low back pain (LBP) is a growing problem. Prior Experiences of Behavioral Health Treatment among Uninsured Young Adults Served in a Psychiatric Crisis Setting.

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Thus, STAT3 also plays a role in the recruitment of the transcriptional activators p65 and IRF1, and the displacement of the transcriptional repressors p50 and IRF2 from the CXCL11 promoter also appears to regulate the induction of CXCL11 gene transcription. RSa cells transfected with sense HSP27 cDNA showed slightly lower sensitivity to UVC-induced cell death than the control cells transfected with a vector alone and much lower sensitivity than RSa cells transfected with the antisense HSP27 cDNA. Histo- and bio-chemical observations on -glutamyl transpeptidase in liver diseases.

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Its antiatherosclerotic activity is believed to result from lipid-modifying effects, including its ability to decrease LDL cholesterol and increase HDL cholesterol levels in plasma. Bacteriological Improvements Obtained by the Practice of Break-Point Chlorination. In this study, we provide evidence that calpains also modulate membrane protrusion activity in fibroblasts.

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It has been registered the high level of de novo cases with 17p11.2-duplication. n-3 PUFA supplementation can reduce AF vulnerability in a new canine pacing model of atrial cardiomyopathy. Effect of inflammatory attacks in the classical type hyper-IgD syndrome on immunoglobulin D, cholesterol and parameters of the acute phase response. A method is described that could be of potential use for the rapid ultrastructural identification of abnormal and fragmented elastic fibers in very small wet samples of dermal biopsies from patients affected by Pseudoxanthoma elasticum (PXE).

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Little attention has been paid to the possible importance of these factors for survival. Reductions in portal pressure by selective beta 2-adrenoceptor blockade in patients with cirrhosis and portal hypertension. Deficient Phagocytosis Among HIV-1 Infected Adults Over Time Even in HAART Setting.

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Irinotecan (CPT-11), another camptothecin derivative, has demonstrated clinical activity in patients with 5-fluorouracil (5-FU)-refractory colorectal carcinoma. 335 cross-country skiing accidents which occurred during the last five skiing seasons, are evaluated. Regression of cancer of the urinary bladder following uretero-intestinal anastomosis. Four simulation studies were conducted and showed that the present model has the competence to operate as several different types of learners in various plausibly real-life situations.

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Here, we identified miR-26a and -26b as key regulators of human white and brite adipocyte differentiation. Immunohistochemical study of angiogenic factors in endometrium and endometriosis. An epidemiological evaluation of 1098 acute poisoning cases from Turkey.

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To test this hypothesis, EEG theta rhythm and ensembles of CA1 pyramidal cells and interneurons were recorded from the extreme dorsal and middle portions of the hippocampus. The aims of this study were to investigate the negative action of leptin on some intraovarian ovulatory mediators during the ovulatory process and to assess whether leptin is able to alter the expression of its ovarian receptors. Surface plasmon resonance experiments revealed that 3 forms a stable complex with the target enzyme. The chemokine receptor CCR5 is the major coreceptor used for SIV entry.

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Mortality statistics in immigrant research: method for adjusting underestimation of mortality. We previously demonstrated that transverse propagation of excitation (cardiac action potentials simulated with PSpice) could occur in the absence of low-resistance connections (gap--junction channels) between parallel chains of myocardial cells.

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The present in silico study provides new and important insights into the workings of the HIV-1 protease at the molecular level, supporting the recent hypothesis that the protease primarily recognizes a conformation rather than a specific amino acid sequence. A national longitudinal study of the psychological consequences of the September 11, 2001 terrorist attacks: reactions, impairment, and help-seeking. A lower concentration of heparin (2,500 IU/ml) prevents catheter thrombosis as effectively as a standard one (5,000 IU/ml). Screws placed in Zone 1 (the anterior colliculus) did not contact the posterior tibial tendon in any specimens.

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The frequency of combined TT/ID and GG/ID genotypes of MDM2 T309G and I/D polymorphisms was lower in the patients with SLE and was associated with a lower risk of SLE. Therefore, bilharziasis usually only is considered after tuberculosis, the main differential diagnosis, has been excluded.

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Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. Impact of different domains of physical activity on cause-specific mortality: a longitudinal study. Using an embryonic zebra fish developmental assay, we found that while cyclopamine exposure caused HPE-like defects, exposure to one of these dietary compounds, solanidine, did not. Use of a scanner to register the results of enzyme immunoassay in the standard microplates

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LIMD1 interacts with retinoblastoma (Rb) and is involved in Rb-mediated downregulation of E2F1-target genes. The glyceraldehyde-3-phosphate dehydrogenase (GPD) gene of Lentinus edodes was isolated from a genomic DNA library and cDNA corresponding to this gene was isolated from a mycelium cDNA library. Evaluation of an ultrasound program (intermediate obstetric and emergency medicine) for Australian rural and remote doctors.

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Effects of the traditional Japanese medicine Unkei-to on the corticotropin-releasing factor-induced increase in locomotor activity. Therefore, LAM will become increasingly popular in the study of diverse agriculturally or ecologically relevant plant species.

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Mucopolysaccharidosis type I (MPS I) is a lysosomal disease due to mutations in the gene encoding alpha-l-iduronidase (IDUA) leading to variable clinical phenotypes with progressive severe organomegaly, bone and neurological involvement in the most severe forms. Between 1985 and 1996 203 patients have been operated on for adrenal disease including 21 patients with incidentaloma. These schools paid little attention to actual biological science, and as a result philosophy of biology languished in a state of futility for much of the twentieth century. We sought to investigate the relationship between race/ethnicity, access, satisfaction, and regular mammogram and Papanicolaou test receipt in 5 racial/ethnic groups. P2X1 was highly induced in rat facial motoneurons after nerve resection, which causes slowly occurring neurodegeneration.

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Sequence-specific cleavage of human telomere DNA by G-quadruplex formation. Most individuals of the parental species can no longer be considered as pure-bred individuals because most were classified as backcrossed hybrids. Previously we demonstrated that heat shock protein 27 (hsp27) overexpression confers resistance to the chemotherapeutic agent doxorubicin in MDA-MB-231 breast cancer cells.

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Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. Patent medicine vendors, community pharmacists and STI management in Abuja, Nigeria. Breast cancer cell line MDA-MB-231 cells were used in this study. Discriminant properties of commonly used quality of life measures in heart failure.

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The health outcomes that were considered were changes in blood pressure, cardiovascular morbidity, and cardiovascular and/or all-cause mortality rates. It indicates that ASPN is an important regulator in the etiology of DDH. Both H3K79me2 and H3K79me3 decreased soon after fertilization, and the hypomethylated state was maintained at interphase (before the blastocyst stage), except for a transient increase in H3K79me2 at mitosis (M phase). Those components are specifically correlated with both overt and subjective dimensions of schizophrenic psychopathology.

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Heavy-atom derivatives have been obtained with both forms and electron-density maps calculated. Experimental design and the signalling properties of fluctuating asymmetry The objective of this study was to compare the response of two disposable clinical catheter systems: water-filled and air-charged, to controlled pressure signals to assess their similarities and differences in pressure transduction.

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Relativistic basis sets of double-zeta, triple-zeta, and quadruple-zeta quality have been optimized in Dirac-Hartree-Fock calculations for the 4s, 5s, 6s, and 7s elements: K, Ca, Rb, Sr, Cs, Ba, Fr, and Ra. The aim of this part of the study was microscopic evaluation of repair tissue thickness and its integration with surrounding cartilage, after autologous chondrocyte transplantation. Vincristine is a key agent for the treatment of acute lymphoblastic leukemia (ALL) and other lymphoid malignancies.

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This Special issue of Biotechnology Journal explores recent advances in the emerging field of stem cell engineering, with a focus on applying engineering approaches to understanding stem cell biology and enabling translation of stem cells to commercial and clinical products. Molecular cloning and functional characterization of a glucose transporter (CsGLUT) in Clonorchis sinensis.