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These methods have been implemented in PROLOG in a knowledge management system which is being used in the development of intelligent drug information and medical decision support systems. Understanding the role and mechanism of raised hepcidin and so reduced iron availability during infection is critical to establish evidence-based guidelines for management of malaria anemia. The relatively selective alpha 2-adrenoceptor agonists clonidine, UK-14,304, guanfacine and lofexidine caused significant hypotension and bradycardia when given intracerebroventricularly (i.c.v.).

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Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development. Mutation in NRAS in familial Noonan syndrome--case report and review of the literature. A direct causal role of central nervous system (CNS) viral infection in MS has largely been discounted following repeated failures to demonstrate virus within the oligodendrocyte-myelin unit. Significantly, the combination of vorinostat and tadalafil was more effective than each drug alone, both against the symptoms and in terms of disease modification, and importantly, these effects persisted after a 4-week washout period.

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Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation. Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease.

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Activation of the next determinant (or reactivation of the previous one) occurs only after the next cell division, only one determinant being activated (reactivated) in each cell cycle. We describe a six-compartment kinetic and dynamic physiological model of induction of anaesthesia with thiopental. AREA-INTENSITY RELATIONS WITHIN THE FOVEA FOR FLICKERING WHITE AND PART-SPECTRUM TARGETS. Brainstem auditory evoked potentials: intraoperative monitoring technique in surgery of posterior fossa tumors.

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Effects of humic acid concentration on the microbially-mediated reductive solubilization of Pu(IV) polymers. Positive QFT in the setting of negative TST frequently anticipates a TST boost. Patients whose symptoms include widespread, diffuse musculoskeletal pain are commonly referred for rheumatological evaluation, even when the underlying cause may lie out with the remit of rheumatology.

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However, it is one of the least available macronutrients due to its high fixation in the rhizospheres. The results show that immunohistochemical analysis of beta-catenin expression may be used as an indicator of aggressiveness in renal cell carcinoma.

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Therefore, anatomic data characterizing the palatal midline region are of clinical importance. THE AMERICAN MEDICAL ASSOCIATION: ITS ORIGIN, PROGRESS AND PURPOSE. Inadequate infrastructure for donor referral programmes and the lack of support for tissue transplant co-ordinators however, continue to limit the availability of donor tissue.

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Vascular trauma and the pathogenesis of the Koebner reaction in psoriasis. This rim of cortex has a tendency to fall away from the dura into the cavity during and after intracranial surgery, due to the lack of support, once the pressure in the fluid cavity has been reduced. The study aimed to investigate the anatomy of the lateral nasal wall to provide a set of measurements among some important anatomical landmarks and to reveal the relationship between them. The MSCs underwent co-culture with conjunctival epithelium in the manner without cell-to-cell contract.

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These results highlight important differences in the regenerative abilities of embryonic and adult DRG neurons when grown on physiologically appropriate substrata. Even tumour patients with initially normal or slightly increased basal PP levels showed this secretion pattern.

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The lowest applied flow-rate of the mobile phase was maintained at 50 nl/min with a sample load of 90 fmol. This may be due to circumstances related to the disease necessitating therapy as well as due to a pharmacological effect. The indicator strain plays a significant role in bacteriocin assays. The unresponsiveness to LPS detected in C57BL/10Cr mice is inherited as a recessive trait and is determined by an autosomal gene linked to theMup-1 locus on chromosome 4. To this effect, the NMR-based method comprising a probabilistic model of protein conformation in conjunction with the molecular mechanics and quantum chemical computations was used for determining the ensembles of conformers matching the NMR requirements and energy criteria.

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This study demonstrated that analysis of the transposable intron region in the 25S rRNA gene may be useful in helping to differentiate C. Effects of the proteases trypsin, papain and actinidin on Actinomyces monospecies biofilm and multispecies biofilm that was reconstructed using a plaque sample from the tongue coating were investigated using the microtiter plate method.

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Substantial variations in the prevalence of risk factors, chronic conditions, and use of preventive services among different minority populations and in communities within the same racial/ethnic population provide opportunities for public health interventions. In this report, the authors present the results from a study of patients with unresectable oropharyngeal squamous cell carcinomas who were treated on a protocol of hyperfractionated radiation and high-dose intraarterial cisplatin (HYPERRADPLAT) at the University of Kentucky.

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Recently, two representative mammalian stress-activated kinases, the JNK and p38 MAP kinases, have been implicated in determination of cell fate by modifying the life, death and differentiation signals. The maximum standardized uptake value (SUV(max)) of the primary tumor lesion (P(max)), the SUV(max) of all the tumor lesions, including the primary tumor lesion and metastatic lesions (T(max)), and the uptake ratio of T(max) to mean SUV of normal liver tissue (T(max)/L(mean)) were calculated and tested as prognostic factors. The effect of an aqueous extract of the roots of Asiasari radix (ARAE) on an in vivo and in vitro IgE production was investigated. S 5B/Pl rats, which are resistant to dietary obesity, have a more rapid turnover of norepinephrine in interscapular brown adipose tissue and heart and a greater increase in the concentration of norepinephrine in brown fat when eating a high-fat diet than do Osborne-Mendel rats, which are sensitive to fat-induced obesity. Eucalyptus gomphocephala was therefore not seasonally isohydric.

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After 3 and 6 months, the frequency and content of GP contact, and adherence to GP consultations and treatment in general were registered. Ciguatoxins (CTXs) contaminate fish worldwide and cause the foodborne illness ciguatera. Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides. However, frequency of neutropenia, duration of mechanical ventilation, and neonatal sepsis rates were found to be significantly higher in the study group compared with those of the control group. It is of note that the metabolites of quercetin enter erythrocytes and donate electrons to the PMOR as the parent compound.

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We combined epidemiological information, whole-genome sequence data, and ultradeep sequencing approaches to provide the most complete characterization of the evolution of HPAI from LPAI viruses undertaken to date. In our case of a patient with recurrent major depressive disorder, subthreshold anxiety disorder and addiction to alprazolam, topiramate appears to be efficient and safe in alprazolam withdrawal. CLINICAL EXAMINATION OF THE HEMOSTYPTIC EFFECTS OF ESTRIOL SUCCINATE To explore analgesic effects of fentanyl and butorphanol on incisional pain in rats and to investigate the pharmacological mechanism of combination.

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An alternative hypothesis is that the regulatory unit in nucleolar dominance is the NOR, rather than each individual rRNA gene, in which case NOR localization may be essential for rRNA gene silencing. After 1 month, Mycobacterium bovis was isolated from these tissues. Report of a CIANS Working Group concerning standardisation of procedures, and the need for collaborative studies on transcultural validation. These inhibitors significantly suppressed the HHE-induced NO levels to a basal level.

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Property offences constituted the majority of offences in all groups. Treatment of scapulo-humeral periarthritis with alpha-chymotrypsin and rehabilitation Recent studies suggest that alterations in autonomic neural activity may mediate the obese state observed following ventromedial hypothalamic (VMH) lesion. The clinical picture bears striking similarities to the syndrome of subacute combined degeneration associated with vitamin B12 deficiency. Women have more spells of sickness absence than men but the reasons for this are unknown.

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Platelet-derived growth factor C (PDGF-C) was recently identified as a member of the PDGF ligand family. Subcultures of the susceptible strain in the presence of ribavirin/ ACAA did not lead to the development of resistance to ACAA, ribavirin or their combination.

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Using the analogy of involuntary commitment of the mentally ill, where prediction of dangerousness is based on past behavior, the author points out that testing for HIV antibodies can give a yes-or-no answer to whether a person is infected. Here, we sought to identify low-dose radiation-responsive phosphoproteins in normal fibroblast cells. The prevalence of atherosclerosis increases with age and directly impacts on the workload of both cardiac and vascular surgeons.

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DNA vaccines are able to stimulate both arms of the immune system simultaneously, without carrying the safety risks associated with live vaccines, therefore representing not only an alternative to conventional vaccines but also significant progress in the prevention and treatment of fatal diseases and infections. Diabetes mellitus significantly impacts on the lower urinary tract function. We report 30 patients (27 male and 3 female)--13 after LFLC and 17 after LFLE (including 15 cases of LFLE with epiglottoplastic).

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In vertebrate embryos, positioning of the boundary between the midbrain and hindbrain (MHB) and subsequent isthmus formation are dependent upon the interaction between the Otx2 and Gbx genes. Effect of radiofrequency ablation on atrial mechanical function in patients with atrial flutter.

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Although the relation is not causal per se, the findings support the hypothesis of a complication-induced, compromised immunity rendering patients more susceptible for recurrent disease. In this paper we report our reanalysis of Syk expression in subpopulations of murine and human thymocytes by intracellular staining and flow cytometry using anti-Syk mAbs. The predicted transmembrane domain in 2a NS4B was shown to be responsible for the decreased sensitivity to cGAMP.

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Colloidal Rings by Site-Selective Growth on Patchy Colloidal Disc Templates. Comparative pathogenesis of experimental infections with Salmonella gallinarum in local and commercial chickens. 223 pregnant women were identified in a systematic search of a district. DENV vaccine development is challenging due to the existence of four serotypes of the virus (DENV1-4), which a vaccine must protect against. Agonist induced down regulation and recent evidence for involvement of ubiquitin/proteasome system in this process has been discussed.

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This can lead to overlapping of cyclotron resonances at different harmonics. In contrast, zymography showed a decrease of collagenolytic activity in aortic aneurysm tissue, but an increase in mural thrombus, compared to respective controls. Intimal thickness and the rate of intimal thickening are expressed as functions of shear stress and time based on experimental data. Value of a therapeutic trial to diagnose gastroesophageal reflux disease: step up versus step down therapy. Gassan, Issai, and Mitsuko, vitamin C content of the fruit was much higher than that of Hayward.

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Our method was found to be robust and highly reproducible, giving a direct measurement of pelvic protrusion irrespective of pelvic shape. Identification of human dopamine D1-like receptor agonist using a cell-based functional assay. In view of the many pathophysiologic and pharmacologic similarities between the kindling model and TLE, these data may indicate that PGP overexpression in pharmacoresistant patients with TLE is a result of uncontrolled seizures but not of the processes underlying epilepsy. It was possible to obtain curves for both mid-arm circumference and mid-arm/head circumference ratio in relation to birth weight. Estrogen replacement therapy for Alzheimer disease in postmenopausal women.

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The differences between the measures were related systematically to ownership, geographic location, teaching status, hospital size, and percentage Medicare inpatient days. Phx-1 inhibited the growth of these cancer cells in a dose- and time-dependent manner. It is a recurrent skin condition and persistent hypopigmentation may remain after treatment, causing social problems to those affected. Clinical research of ischemic preconditioning on lung protection 2nd WHO Congress on various immunological problems in the study of leprosy

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Female Sprague-Dawley rats undergoing PBOO surgery were screened for DO by cystometry. Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation.

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We describe the clinical course and biochemical phenotype in 16 children from the Faroe Islands with a homozygous SUCLA2 splice site mutation. Organelle-specific activity-based protein profiling in living cells.

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Ethanol extract of black soybean can stimulate the growth of MCF-7 cells and increase the expression of estrogen receptor-responsive gene, suggesting that the estrogenic effects of BSE are mediated by the estrogen receptor. We present a comprehensive compilation of factors modulating animal responses to humans at increasing levels (from sensory detection and immediate behavioural and physiological reactions, to changes in fitness and population trends), which may help understanding the uncertainty in the patterns.

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In this paper we report on the structural properties of aqueous solutions of bacterial levan utilizing smallangle X-ray scattering and light microscopy. The effects of environmental factors on the incidence of Helicobacter pylori infection in the adult population of the Lublin region. The trunk motion characteristics of 374 healthy people and 335 patients with chronic low back disorders of varying severity were documented as they flexed and extended their trunks in five different planes of motion. In unbalanced chromosomal patterns with deletions of 11q involving bands 11q23-q24 the typical phenotype of 11q- syndrome remains recognizable.

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Framingham risk score (FRS) underestimates risk in young adults. Cognitive function was impaired, particularly information-processing speed, and decreased cognitive function was correlated with apathy and depression in Japanese patients with MS.

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