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Klarithran (Clarithromycin)
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Clarithromycin

Klarithran is a semisynthetic 14-membered ring macrolide antibiotic. Klarithran binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Klarithran has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)

Other names for this medication:
Clarithromycin, Biaxin, Abbotic, Aeroxina, Biclar, Binoclar, Bremon, Clabel, Clamycin, Clarimac, Clarimax, Clarimed, Clarimycin, Claripen, Claritt, Clariva, Clariwin, Clarix, Claromycin, Claron, Cleron, Emimycin, Euromicina, Finasept, Fromilid, Infex, Kailasa, Kalixocin, Klabax, Klabet, Klabion, Klarimac, Klarimax, Klarithran, Klax, Klaz, Klerimed, Kofron, Krobicin, Lekoklar, Macladin, Maclar, Macrobid, Macrol, Monozeclar, Naxy, Synclar, Taclar, Veclam, Vikrol, Xylar, Zeclar, Zeclaren,

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The Big Bone Lick area in Kentucky, the first widely known collecting locality for vertebrate fossils in North America, is being investigated for further faunal and geologic evidence. Moreover, in comparison to photons, carbon ions offer an increased relative biological effectiveness (RBE), which can be calculated between 2 and 3 depending on the HCC cell line as well as the endpoint analyzed.Japanese Data on the evaluation of carbon ion radiation therapy showed promising results for patients with HCC. The computational protocol leveraged docking and high level atomistic models to improve enrichment.

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Reduced PCR sensitivity due to impaired DNA recovery with the MagNA Pure LC total nucleic acid isolation kit. These biochemical and genetic data indicate that Rtt106p is a previously uncharacterized histone chaperone connecting S phase to epigenetic inheritance. We argue that mutagen-based methods, if reliably implementable, can elucidate correlations amongst genes, and determine which sets of genes correspond to redundant pathways in the cell. Subsequent antigen presentation from macrophages to lymphocytes developed autoimmune uveitis. Immunoreactive VIP was detected in the gallbladder lumen and in the arterial blood and venous effluent from the gallbladder in fasting cats.

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Across multiple studies, obesity has been associated with an increased risk of higher grade disease and prostate-specific antigen (PSA) recurrence after radical prostatectomy (RP). Proceedings of the Balkan School of Oncology second seminar, 6-8 September 2007, Volos, Greece. When the gland is stimulated by TSH, droplets are formed from colloid derived from the lumen (phagosomes), and hydrolytic enzymes are transferred from granules to the droplets.

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Good tolerance to the stent was documented, with minimal side effects similar to those that would be observed in human subjects after endotracheal intubation. Socio-demographic information, drinking and substance use habits, drinking status, craving and affective temperament traits were assessed. Bioreactors capable of exerting forces on cells and tissue constructs within a controlled culture environment are needed to provide appropriate mechanical stimuli. ent-Kaurene is the key intermediate in biosynthesis of gibberellins (GAs), plant hormones. coronatum Kent, 1881 represent different sections of the genus Pleuronema (Ciliophora: Scuticociliatida).

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Clusters were tested for significant differences by location, reason for visit, age, education, marital status, ethnicity, insurance, history of cancer, and income. The cytotoxicity of polysaccharide-based hydrogels and solutions was studied in vitro after 48h of indirect exposure of the materials with vascular smooth muscle cells. Endoplasmin is a molecular chaperone of the heat-shock protein 90 class located in the endoplasmic reticulum and its activity is poorly characterized in plants. Effect of coil packing proximal to the dilated segment on postoperative medullary infarction and prognosis following internal trapping for ruptured vertebral artery dissection.

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Clinicopathogenetic considerations on hormonal urinary incontinence in women Formalin is a commonly used fixative to preserve the cellular architecture of cells and tissues and to prevent degradation from proteases and nucleases. This investigation showed that a young child can transmit Mycobacterium tuberculosis to a large number of contacts. Recent studies reveal an increasing incidence of orofacial injuries in sports, especially hockey, and physicians must be prepared to accept a role in the campaign to prevent these injuries which are most common at ages 11 to 18. A new generation of sterile and radiopaque impression materials: an in vitro cytotoxicity study.

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Postnatal Outcomes of Fetal Supraventricular Tachycardia: a Multicenter Study. The heart-lung with an artificial pulmonary membrane of Andre Thomas In this study, we developed a very simple and fast method for the determination of enzyme inhibition using Schizosaccharomyces pombe strains that functionally express either human CYP17 or CYP21. The purpose of this study was to estimate cancer incidence for American Indians in Minnesota.

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Expressed Emotion was measured with the Five-Minute Speech Sample (FMSS). Failure of patients with metastatic non-seminomatous germ-cell tumours to achieve a complete response to initial therapy is shown to be a poor prognostic indicator. As both PAR(1) and PAR(2) have been implicated in the modulation of nociceptive mechanisms, we investigated the expression of PAR(4) in sensory neurons and the effects of its selective activation on nociception. The results suggested that as the calcium concentration in the medium decreased manifestation of osteoclast cells increased, and as the degree of mineralization of E1 cells advanced, the number of manifestation of osteoblast cells decreased.

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Durability of extensive Class II open-sandwich restorations with a resin-modified glass ionomer cement after 6 years. As no correlations were found with the albumin ratio, and no correlations between CSF and serum levels of the cytokines were found, these changes in the CSF cannot be explained by a systemic overproduction of cytokines. To further characterise the biological role of miR-200a expression in CRC, in vitro miR-200a inhibition and overexpression were performed and the effects on cellular growth, apoptosis and epithelial-mesenchymal transition (EMT)-related gene expression were explored. To date, we have observed more than 150,000 person-years in male foundry production workers. Differences in tumor biology between African-American men (AAM) and white men were assessed from a large clinical biopsy series.

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Case of primary bronchial fibrous inflammation in a 5-years-old boy Brompheniramine and the cardio-vascular effects of norephedrine and noradrenaline. Provocative stimulation tests for GH assessment have poor reproducibility and can often elicit false positive results in normal children.

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Will anatomical tumor classification become history as we make way for molecular characterization in oncology? PhosphoSer249 was sensitive to acid phosphatase treatment of native 20S proteasome. Amplification of target DNA from only viable cells in a suspension with dead cells was selectively accomplished by first treating the cells with 1 microg/ml of EMA. The association of central hypothyroidism and VACTERL-H has previously not been reported. In placebo-controlled studies in children, LAIV was 73 to 93 percent efficacious, and protection lasted more than 12 months.

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The nutrition transition and its health implications in lower-income countries. This study gives better quantitative and qualitative evidence about the effects of tobacco smoking on the occurrence of pneumonia in the adult community. Socio-demographic data and clinical information were collected from the patients and their hospital records were reviewed. Educational programmes and rotation policies have not been evaluated sufficiently in the literature. The average ratings, excluding those from the index month, differentiated patients who had incidents from those who did not.

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The drug produced a drop in the heart rate, cardiac index and a slight decrease of total peripheral resistance, due to albetol simultaneous alpha- and beta-blocking action. Penile incarceration injury by heavy metallic ring is a rare genital injury.

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Mean arterial pressure heart rate, the total amount of propofol, time of recovery of spontaneous ventilation, extubation and eye opening in response to verbal stimulus and analgesic requirement were recorded. Lobeglitazone showed a favorable balance of efficacy and safety during the extension study. Human growth hormone (hGH) has been shown in some studies to have anabolic effects on bone, but hGH effects on bone in patients with SBS are unknown. The ultimate goal when closing dental diastemas is to establish an adequate interproximal contact, and to achieve an esthetic emergence profile of the respective teeth, with the interdental papilla filling the space underneath the contact area. As a means of establishing the pathways that regulate secondary metabolite production by this important bacterial genus, the model species Streptomyces coelicolor and its relatives have been the subject of several genetic screens.

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Following the transfusion of 4 U of blood and continued hematochezia, a colonoscopy was performed. Metal-induced toxic effects, which might possibly affect the yield of the plants, were also studied.

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This may be an important addition to indirect defensive effects. These quinoids markedly inhibit respiratory enzymes and protein synthesis.

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The present study was undertaken to characterise the phosphodiesterases (PDEs) present in brown adipose tissue (BAT) of Zucker rat pups and to determine whether the capacity for degradation of cyclic nucleotides was affected by the fatty genotype. Explicitly intruder-free valence-universal multireference coupled cluster theory as applied to ionization spectroscopy.

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Anesthetic antagonism of the effects of high hydrostatic pressure on locomotory activity of the brine shrimp Artemia. The C-kinase activity in late pregnancy was 6 times higher than that of mid pregnancy.

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Risk Factors Associated With the Presence of Unruptured Intracranial Aneurysms. Pre-hospitalization treatment with Abciximab in the preparation of patients for primary angioplasty in the acute phase of myocardial infarct. Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines. All postpubertal patients should have a low vaginal swab to diagnose candidiasis rather than treating empirically. These clinical findings could be explained by the new classification of brain malformations, which takes into account the role of neural crest in Waardenburg syndrome.

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Non-invasive markers could prove valuable in monitoring response to treatment during clinical trials. End-tidal carbon dioxide pressure was measured by using three capnometer/cannula combinations (oxygen at 4 l/min): (1) a mainstream capnometer with oral guide nasal cannula, (2) a sidestream capnometer with a nasal cannula that included an oral guide, and (3) a sidestream capnometer with a standard nasal cannula. Optimization of interfaces in inorganic-organic device systems depends strongly on understanding both the molecular processes that are involved in surface modification and the effects that such modifications have on the electronic states of the material. The ectoparasite might also serve as a vector and reservoir of pathogenic bacteria. These results show that the cut-off point of 0.8 established for the complexed-to-total PSA ratio is the same for men of all ages, and that the use of this ratio may avoid many negative prostate biopsies, confirming that PSA: alpha 1ACT is a potential marker for differential diagnosis of prostate carcinoma and BPH.

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This 145-kDa protein is induced to associate with Shc by multiple cytokines and may play an important role in the negative regulation of immunocompetent cells mediated by FcgammaRIIB receptor. Currently, most tag SNP selection is based on two-marker (pairwise) linkage disequilibrium (LD). The case study revealed a number of themes consistent with reports in the literature and reflecting cited best practices.

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Diagnosis and management of urinary tract infection in children. The central incident about NVP in Woman were aggravation of physical condition and irritability of emotional state. CRITERIA FOR TREATMENT OF INJURIES OF THE MEDIAL COLLATERAL LIGAMENT OF THE KNEE Tumours were peripheral in 51 cases and in a juxtahilar position in 10 cases.

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However, it has not been clarified during various levels of propofol anesthesia. It can be argued that an integrated analysis of any neural system cannot be performed without the aid of a close interaction between experiments and modelling. The engineering design has been fully assessed using finite-element techniques to predict the deflections of critical parts of the structure.

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ADMINISTRATIVE HANDLING OF THE NARCOTIC ADDICT: ITS BENEFITS AND DANGERS. Our data show that NSCs derived from human fetal cortex and striatum exhibit region-specific differentiation in vitro, and survive, migrate, and form mature neurons to the same extent after intrastriatal transplantation in newborn rats. So it is the appropriate approach to treat type C fractures of the distal femur. A transgenic mouse expressing kinase-active FRK under control of the insulin promoter (RIP-FRK) was studied with regard to islet endocrine function and vascular morphology.

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It has been hypothesized that remifentanil would provide a safe anesthesia with no impact on myocardial function and with positive effects on extubation time and mobilization. miR-126 in human cancers: clinical roles and current perspectives. It is now widely understood that the molecular triad--receptor activator of NF-kappaB ligand (RANKL), its receptor RANK, and the endogenous soluble RANKL inhibitor, osteoprotegerin (OPG)--play direct and essential roles in the formation, function, and survival of osteoclasts.

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Bronchopulmonary dysplasia (BPD) is the most frequent serious complication in preterm infants. The authors report an unusual surgical treatment for an aneurysm on the left peripheral posterior inferior cerebellar artery (PICA). In the present study, the authors assessed the ability of CI subjects to perceive simultaneous modulation frequencies based on direct electrical stimulation.

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Occupational skin disease in workers from the electronics industry in Singapore. Comparison of fragments obtained during enzymatic digestion and by reduction and alkylation.

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A new semiquantitative method for comparing brain tumor uptake of Tc-99m sestamibi and TI-201. He was started on chemotherapy but had a progressive downhill course. This study provides the first direct evidence that hydrostatic forces may contribute to the development of re-expansion pulmonary edema. gambiense sleeping sickness: observations on drug resistance in the trypanosomes of the French Cameroun.

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A new type of specific DNA contact is seen, in which a carboxy-terminal helix is deeply embedded into an enlarged minor groove without bending the DNA. It was shown that strongly ordered CF3 groups dominate the surface of the TFMBA, and the vibrational modes of this functional group are strongly coupled to the benzene ring of the benzyl alcohol.

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Groups of 40 male and 20 female rats were exposed to TMA by inhalation at target concentrations of 0, 10, 30, 100, and 300 micrograms/m3, 6 hours per day, 5 days per week, for 2 weeks. Low affinity uptake systems function when their substrates are in greater supply. Solvent-free vapor-phase photografting of acrylamide onto poly(ethylene terephthalate). Clinical outcome of native valve infective endocarditis in Khon Kaen: 1990-1999.

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The in vitro production of beta2-M by B-CLL cells from 27 patients was investigated. Evidence for its involvement in phytoecdysteroid biosynthesis in Polypodium vulgare. Patients initially harboring occult carcinoids may also exhibit severe hypercortisolism and those harboring tymic carcinoids had poor prognoses when compared with bronchial carcinoids and pheocromocytomas. These new metabolites were minor constituents compared with aminoglutethimide and with the previously identified major metabolites 3-(4-acetylaminophenyl)-3-ethylpiperidine-2,6-dione and 3-(4-hydroxylaminophenyl)-3-ethylpiperidine-2,6-dione. Mu opioid receptor mutant, T394A, abolishes opioid-mediated adenylyl cyclase superactivation.

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In the case of sinusoidal perturbation, the transition time from the chaotic to regular state has a definite duration that depends on the values of the perturbation parameters. Mail-order microfluidics: evaluation of stereolithography for the production of microfluidic devices. On a therapy study of multiple vitamin deficiencies inchildren of a mountain valley Alkinyl derivative 10 emerged as the most active (in MES and ScMet tests) of all the compounds tested.

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Motor task imaging revealed increased rCBF in the cerebellum and reduced rCBF in anterior regions of the default mode network. In fact, a bioinformatics analysis of mammalian proteins that express a heparin/HS-binding motif and are associated with the immune system identified 235 candidate proteins, the majority having an intracellular location. A new focus in the field of emotional memory is the study of sex-related differences.

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These findings suggest that short-term FD selectively decreases liver ODC responses to certain agonists including alpha and beta adrenergic agonists by postreceptor mechanisms. Cerebral venous thrombosis remains an important and sometimes an elusive cause of strokes.

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The prevalence rates of refractive errors among children, adolescents, and adults in Germany. Valacyclovir and Acyclovir Neurotoxicity With Status Epilepticus. A general surgery department of a university referral hospital in Nanjing, China.

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No global optimal design exists and local optimal designs depend on scenarios gasec 20 mg opinie toyota comprising the true disease model and the association between the phase-one and phase-two information. A crucial next step is the integration of knowledge gleaned from observations in disease states with normal physiology to generate an explanatory model for craniofacial development. Elbow arthroplasty remains a valuable option for deformed and ankylosed elbows especially in the demanding patients with crippling deformity of the elbow. Moreover, brown skin showed a high concentration of quercetin aglycone and calcium, and top-bottom showed high concentration of minerals.

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The electrodiagnostic differentiation between campylobacter jejuni treatment azithromycin pronator teres syndrome and entrapment of the median nerve at the ligament of Struthers is generally thought to be aided by the absence of electromyographic (EMG) findings in the pronator teres muscle in pronator syndrome. Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis. Native hepoxilins (Hx) A3 and B3 as well as their synthetic cyclopropane analogs, HxdeltaA3 and HxdeltaB3 are inactive on their own in causing changes in vascular permeability in rat skin measured by leakage of plasma-bound Evans Blue dye. sp., a tongue worm (Pentastomida: Porocephalida: Sebekidae) infecting softshell turtles, Apalone spp. On some particularities in the treatment of angina pectoris with iproniazid (marsilid)

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Individual accounts highlight the diversity and complexity of experience of older people who attempt suicide. In this study, we investigated the role of nuclear factor-kappa B (NF-kappaB) and signal transducers and activators of transcription 3 (STAT3) in lipopolysaccharide (LPS)-induced IL-12p40 gene expression in bone marrow derived-dendritic cells (BMDCs) isolated from wild-type (WT) and IL-10(-/-) mice. Comparative assessment of the activity of beta-carotene, retinoyl-beta-D-glucuronide and retinoic acid on growth and differentiation of a human promyelocytic leukemia cell line HL-60. This is not endep tablets amitriptyline for cats surprising given that most of the signal transduction machinery is membrane-associated and therefore lipid-related.

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2), The decay of the activated state of the thin filament followed the time course of tension more closely in an ADP-dependent manner. In the second part, the theoretical reasons for supporting or contraindicating such combinations are discussed in the light of pharmacological data. Long-term efficacy and safety outcomes of modified gabateva 600 mg fiyat (simplified) MVAC (methotrexate/vinblastine/doxorubicin/cisplatin) as frontline therapy for unresectable or metastatic urothelial cancer. Cytoskeletal structure and recovery in single human cardiac myocytes.

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They were asked to identify each lesion, the average thickness of the lesion, and the axis at which the OCT was taken. Finally, NPC fibroblasts exhibited a gene expression profile indicative of oxidative stress. The increase in the levels of serum IL-6 in hyperthyroidism is not paroxat 10 mg nebenwirkungen related directly with bone resorption seen in hyperthyroidism.

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The A353V, but not the G402E, mutation led to severe destabilization of telomerase RNA, a reduction in telomerase activity, and a significant continuous loss of telomere length with increasing numbers of cell omnicef side effects dizziness symptoms divisions during in vitro culture. However, vertebrate immune defense is a complex system that consists of three components. A brief overview of the inherited dyslipidemias, a review of the currently available means of transferring genetic material in vivo, and a discussion of two examples of conditions in which gene therapy may be useful--familial hypercholesterolemia and reduced high-density lipoprotein cholesterol syndromes--are presented. The renin-angiotensin system: the role of inhibitors, blockers, and genetic polymorphisms in the treatment and prevention of heart failure. A computer system can provide an objective and quantitative evaluation of skin lesions, reducing subjectivity in the diagnosis.

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To study the feasibility of using primarily thinned free groin flap in the treatment of recurrent neck contractures in children. Of 79 articles and abstracts, 5 met inclusion criteria and 3 more could be added after investigators provided additional information. Contribution of CSF analysis to the diagnosis of inborn errors of metabolism in adult patients In clonogenic phase 2 cultures, the number of colonies did not significantly differ between normal cultures and DBA, in the presence or absence of dexamethasone, and at both low and high Epo concentrations. clopidogrel side effects insomnia movie Current-generation DES have zotarolimus, everolimus or biolimus as antiproliferative drugs.