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In a retrospective study we analyzed our results of ACL reconstructions with a patellar tendon graft. This may have been GH-mediated, since exogenous GH similarly increased the incorporation of ((3)H)-thymidine into cultured testicular cells and increased their metabolic activity, as determined by increased MTT reduction.

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The biological mechanisms that govern the outcomes of radiotherapy need to be completely understood before rational application and optimization of such adjuvant biotherapies with radiotherapy. This study also demonstrates discrepancies between the literature with regards to various methods of centrifugation, variable cell count concentrations, and lack of standardized outcome measures. Glioblastoma multiforme is the most devastating tumor in the brain. Purified products were analyzed for heparan sulfate binding properties.

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Practical synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate and resolution of enantiomers. No significant differences in escape latency were observed in the visible probe test among the ZD, EZD, and normal-fed control at 4 weeks (CT4w) groups in which body weight was standardized to that of the EZD group, or in the daily reduction in latency between the normal-fed control and CT4w groups.

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The presence of the additional circular wire significantly increased the compressive strain. The present studies were performed to identify the major mechanism by which polysaccharide impairs lymphocyte proliferation, since capsular polysaccharide has the potential to affect the development of T-lymphocyte responses by stimulating production of interleukin-10 (IL-10), inhibiting phagocytosis, and inducing shedding of cell surface receptors. Tyrosinase activity in primary cell culture of amelanotic melanoma cells.

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Clinical variables affecting the pregnancy rate of intracervical insemination using cryopreserved donor spermatozoa: a retrospective study in china. However, if VLPP is considered vital to planning treatment, UD studies will still be required, since no question could estimate the severity of incontinence as determined by serial VLPP measurement. Halofuginone (HF) has been proven to inhibit the formation of fibrosis in various animal models and human diseases. Chemotherapy should be included in the multi-modality treatment of PBL. Sodium hyaluronate (SH) is a promising submucosal injection solution during endoscopic mucosal resection, but its high cost is an obstacle to more widespread use.

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This study compared outcomes of the Cox-Maze IV (CMIV) in patients with lone AF to those with AF and MV disease. In this study, we addressed whether post-translational modifications of RUNX2 control its activity during mitotic exit. Although the goals of therapy, such as to improve symptoms and to prevent both recurrent attacks and complications, are clearly established, the standard approach remains still debated.

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Naturally occurring neuron death during postnatal development of the gerbil ventral cochlear nucleus begins at the onset of hearing. Most, if not all, treatment protocols rely on the PUVA-induced erythema as a guideline for UVA dosimetry. Alterations of the P53 or Rb gene are among the most frequently observed genetic changes in primary lung cancer. To examine longitudinal outcomes, rate of and reasons for discontinuation, and predictors of insulin pump success in a cohort of youth initiating pump therapy.

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ATP-TCA method is good for patients with cervical cancer because it is sensitive, effective, and individualized. The drug proved safe and well tolerated and its properties are unlikely to produce clinically relevant drug interactions in the transplant recipient. The recommendation from the American College of Obstetricians and Gynecologists is to allow vaginal delivery after one cesarean section. An effective coupling approach is based on a process of standard splicing and tapering between the single-core single-mode fiber and the multicore single-mode fiber. Role of boson-fermion statistics on the Raman spectra of Br2(X) in helium clusters.

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During growth of Escherichia coli on acetate, phosphotransacetylase and alpha-ketoglutarate dehydrogenase are in direct competition for their common co-factor, HS-CoA. Activity of the enzymes of local and overall biological actions was examined in a group of patients who had suffered gastric resection for peptic ulcer. In contrast, the mutant ND4 disrupted mitochondrial cytoarchitecture, elevated reactive oxygen species, induced swelling of the optic nerve head, and induced apoptosis, with a progressive demise of ganglion cells in the retina and their axons comprising the optic nerve.

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Sagittal MRI images showed hindrance to normal posterior shift of the IR pulley from central to infraducted gaze. Analgesic effect was studied using acetic acid-induced writhing in mice and hot plate analgesia in rats while anti-inflammatory activity was investigated using carrageenan-induced paw oedema in rats.

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International collaboration is required to plan and conduct a large-scale multicenter trial in order to better inform clinical practice and public health policy about the optimal management of asymptomatic hyperuricemia in patients with CKD. The results of treatment with Bio-alcamid were good immediately postoperatively, although two patients required further corrective procedures. The capability to obtain quantitative information of a simple way from Raman spectra is a subject of considerable interest. Rest-activity rhythms in small scale homelike care and traditional care for residents with dementia. The multifunctional RNA-binding protein, CUGBP1, regulates splicing, stability and translation of mRNAs.

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Influx of labelled D-glucose into isolated spinach (Spinacia oleracea L. This study additionally implicates a biological role for N-linked glycoproteins in OMVs. These equations may be used in most respiratory chambers and modified to accommodate exercise or specific feeding protocols.

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To determine whether pregnancy outcome can be positively affected if the ovarian stimulation in women with diminished ovarian reserve (DOR) is changed. A higher HSP70 level was also observed on day 30 in F1 confined-juveniles. Sixty six patients with known cirrhosis entered this cross-sectional study. We report our initial experience with laparoscopic nephron-sparing surgery using the TissueLink floating-ball radiofrequency dissector. Propofol plasma-effect site equilibration occurs more rapidly after a bolus than after rapid infusion, based on the electroencephalogram as a drug effect measure, mostly because of misspecification of the pharmacokinetic model in the first minutes after bolus.

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Three groups of women seen were studied: 50 women with screen-detected breast cancers, which were palpable and detected by the nurse-examiner, 62 women with occult screen-detected breast cancers and 353 age matched women with invasive breast cancer from the LRCC prospective database, who served as controls. Females were more likely to have a confidant, although this declined with age whilst increasing with age for males. However, a lack of keratinized mucosa is found in many cases which may have adverse effects on the long-term success of dental implants with microstructured surfaces. A new heart sound, especially a continuous murmur, may be detected during physical examination. The mechanism on how these descriptors affect transdermal permeation is not clear.

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Diagnostic quality and cost effectiveness are key factors in the acceptability of film digitizers to meet these requirements. The seasonal effect on births of children with later childhood-onset Crohn disease is similar to that described for diabetes mellitus type 1, i.e., maximal frequency of births in summer.

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Patients with Hodgkin lymphoma treated with thoracic radiation have an increased incidence of coronary artery disease (CAD). Larger or longer clinical trials may be unfeasible and postmarketing surveillance is not being undertaken systematically enough to ensure safety. These data confirm the possibility of achieving encouraging rates of local control and OS in LACC patients submitted to chemoradiation plus surgery, with a low rate of toxicity and complications.

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Pax6 is a direct, positively regulated target of the circadian gene Clock. Our results suggest that surfactant is an effective vehicle for intratracheal delivery of glucocorticoids. Therefore, customary shinrin-yoku may help to decrease the risk of psychosocial stress-related diseases, and evaluation of the long-term effects of shinrin-yoku is warranted.

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We used a transient co-transfection assay to regulate annexin II expression in human HeLa, 293 and 293T cells, and measured the effects of annexin II down regulation on DNA synthesis and proliferation. Free energy profiles demonstrate that the nonhydrolyzable product of the condensation reaction, dethiacitryl-CoA, forms a particularly stable complex with TpCS but not pig heart CS.

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Normally residing in both neuronal cytosol and mitochondrial intermembrane space, calpain I was found to be activated in neurons after ischemia and to cleave intramitochondrial AIF near its N terminus. The cause of non-gonococcal urethritis remains to be discovered. Foreign bodies in the spine are most commonly traumatic and managed in an acute setting. Recently, it has been shown that components in the fatty stroma in involuting breast can promote metastasis.

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SB-277011-A (20 mg/kg i.p.) itself did not produce significant changes in rCBV, but potentiated the phMRI response to 1 mg/kg i.v. Patients were discharged at a pacing rate of 65 beats per minute after setting of the optimal AV delay. The pneumococcal conjugate vaccine (PCV), licensed in 2000, is highly efficient in preventing serious disease caused by serotypes in the vaccine and also prevents symptomless colonization of the nasopharynx. Further optimization of the UVC procedure, however, is necessary to deal with blood-borne viruses like HIV. Response of embryo axes of germinating seeds of yellow lupine to Fusarium oxysporum.

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The prevalence of microalbuminuria in Extremadura seems to be high either in diabetics or non diabetic hypertensive patients. Old relief printing applied to the current preparation of multi-color and high resolution colloidal photonic crystal patterns.

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Three kinds of magnetite/reduced graphene oxide (MRGO) nanocomposites were prepared by solvothermal, hydrothermal and co-precipitation methods. This chapter first reviews the basic conceptual and methodological underpinnings of the molecular epidemiological approach and then summarizes the main aspects of ExPEC that have been investigated using this approach. A review of thirty cases of rhabdomyolysis-associated acute renal failure among phencyclidine users. Children under 11 years of age with a milder degree of hydrocephalus or who were right-handed also scored significantly better.

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Amino acid coefficients were subsequently derived from the RP-HPLC retention behaviour of these peptides and compared to each other as well as to coefficients determined in the centre of the peptide chain (internal coefficients). Avoidance tests with earthworms and springtails: defining the minimum exposure time to observe a significant response. But quality of life in well-controlled epileptic patients is similar to quality of life in healthy persons. In vivo monitoring of microRNA biogenesis using reporter gene imaging. This may be used to compare populations by estimating abundance and assessing species distribution from this data.

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These patients often present with stridor and require a tracheostomy. FEV1 and FVC were measured before and 20 min after inhalation of 400 microg salbutamol, and skin prick tests performed with three allergen extracts (grass, Der p 1 and cat). Thicknesses of each zone of normal equine cartilage (calculated based on differences in collagen orientation) were equivalent as determined by PLM and FT-IRIS. A quantitative imbalance between matrix metalloproteinases produced by cancer cells and tissue inhibitors of metalloproteinases produced by fibroblasts and other types of cells has been demonstrated to be a causative factor in invasion and metastasis of cancer cells. All of the functional and histologic changes were improved with insulin therapy.

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The authors report a case of a pyocele of the lachrymal sac occurring 60 years after a transantral surgery for a JNA. We also found alterations in the activity of one of the constructs on altering the growth conditions of the HaCaT cell line.

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Using national Medicare claims data from 2000 through 2009, we examined mortality among 3,282,127 patients who underwent 1 of 8 gastrointestinal, cardiac, or vascular procedures. The cysteine protease activity of this organism is a validated drug target as first recognized by the killing of the parasite with the diazomethane inhibitor Z-Phe-Ala-CHN(2) (where Z is benzyloxycarbonyl). In this study, we searched for a specific pattern of SCD in asymptomatic individuals at risk for AD. Examples of issues being addressed are the methods used to estimate incidence and prevalence, the procedures for data collection and its harmonization, the definitions of numerator (cases) and denominator (population at risk), and the modeling of cognitive decline.

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A cross-sectional survey of all women presenting to four primary health care centres in different geographic areas of Lebanon from September 2002 to October 2002. KA may serve as a useful tool in studies assessing central regulation of the autonomic nervous system, and the interrelationship between autonomic activity and seizure-induced neuronal loss. Concentrations of TBT in sediments ranged from 0.89 to 34 ng g(-1) dry wt and those in clams ranged from 1.4 to 56 ng g(-1) wet wt.

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The rates, reaction orders, and activation energies were not dependent on the structure of the active phase. Interaction of several drugs with Tyr 411 anthraniloyl human serum albumin. The most common sequence types identified were ST-2381 (30 isolates), ST-45 (25 isolates), and ST-1225 (23 isolates).

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Rats reared in social isolation exhibit a syndrome of behavioral and biochemical effects indicative of enhanced mesolimbic dopamine (DA) function. Wound healing is a dynamic and complex biologic process that could be accelerated by growth factors.

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An alternative approach for inducing protective immunity with small viral peptides would be the direct targeting of viral epitopes to the immunocompetent cells by DNA vaccines encoding antibody fragments specific to activating cell surface co-receptor molecules. This model suggested that the precise way in which the removal of putative survival factors could affect stem cell survival in culture. Living organisms discovered this billions of years ago, and used carbon as the back-bone for constructing proteins that function according to their structure. However, spontaneous renal cell carcinomas in laboratory rabbits have only been reported once previously.

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Since the 1970s organizations of disabled people have defined disability as a form of oppression. A case of Kearns-Sayre syndrome with autoimmune thyroiditis and possible Hashimoto encephalopathy. Left ventricular assist devices (LVADs) are currently being evaluated as permanent therapy for end-stage heart failure.

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The open-source and free image analysis program ImageJ was used. If the seat could not be tilted back, the maximum pressure in the upright sitting posture with the feet on the ground was significantly lower than sitting upright with the legs supported on a rest. Measurements of characteristics of time pattern in dose delivery in step-and-shoot IMRT. To create a presentation method of TCP and NTCP distributions calculated based on dose distribution for a selected CT slice.

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Enhanced immunogenicity of pneumococcal surface adhesin A (PsaA) in mice via fusion to recombinant human B lymphocyte stimulator (BLyS). Here, we show that the type III effectors, EspG and its homolog Orf3, trigger actin stress fiber formation and the destruction of the microtubule networks beneath adherent bacteria. This is in part due to the difficulties in recognizing these vessels in tissues because of a lack of specific markers. It has been suggested that diencephalic regionalization partially depends on local signaling mediated by sonic hedgehog (Shh).

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Early Life Stress Induced by Limited Nesting Material Produces Metabolic Resilience in Response to a High-Fat and High-Sugar Diet in Male Rats. TRICKS MR angiography of the distal calf and pedal vessels is superior to standard MR angiography regarding the number of diagnostic segments and assessment of the degree of luminal narrowing. It is regarded as the most definitive--but not the sole--form of intraoperative consultation. Alanine-scanning mutagenesis studies targeting residues in the helix 4 region support a direct interaction between this domain of CA-CTD and LysRS.

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Population dynamics and identification of endophytic bacteria antagonistic toward plant-pathogenic fungi in cotton root. Gunshot wounds and facial neuroma are the worst conditions for favorable facial nerve recovery after anastomosis. delayed effects of acute ethanol exposure on cytokine production in a binge drinking model.

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The chemical structure was encoded by constitutional and topological indices. Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD).

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The literature review shows that the negative predictive value of hepatobiliary scanning for acute cholecystitis is nearly 100 percent, while the positive predictive value is also quite good if conditions known to cause false-positive scans are ruled out. Proteinuria in 3 sequential pregnancies following a fourth renal transplant. We present the case of a 7-month old male child who started having recurrent febrile, and thereafter, afebrile seizures, following administration of a vaccination at 3 months. The effect of several neuromediators on succinate dehydrogenase activity

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In 2008 a human papillomavirus (HPV) vaccination programme for cervical cancer prevention was implemented in the UK. Photodissociation of N2O: potential energy surfaces and absorption spectrum.