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MiR-21 inhibits c-Ski signaling to promote the proliferation of rat vascular smooth muscle cells. Three partial responses were observed at dose levels of 50 and 60 mg/m2. High-throughput screening devices such as the BioLector are often applied for screening experiments. A treatment with sedatives is problematic due to possible adverse effects for mother and embryo/foetus.

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Cytochrome c oxidase (COX) stain analysis indicated deficient activity in five patients and subsarcolemmal accumulation in one patient. Scalable Fabrication and Integration of Graphene Microsupercapacitors through Full Inkjet Printing. The coherence of two coupled two-level systems, representing vibrational modes in a semiclassical model, is calculated in weak and strong fields for various coupling schemes and for different relative phases between initial state amplitudes.

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Using three temperamentally different subgroups from a large birth cohort, the authors undertook a longitudinal study of the association between temperament measured in children at 4 and 8 months and IQ assessed at 4.7 years. This technique appears to provide the forensic science community with an operator-free method of reliable GSR particle search and an improved analyst-time-per-case ratio.

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Digital assessment of fetal station was related to the ischial spine. We have described the phenotype of a temperature-sensitive female-sterile mutant, fs (1) K313, nad characterised its yolk proteins. Weedy rice populations from Liaoning are considerably variable genetically and most probably originated from Liaoning rice varieties by mutation and intervarietal hybrids. Taken together, our results establish ubiquitin-mediated proteolysis as a previously unidentified mechanism for irreversibly attenuating the effects of active Src kinase.

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Overexpression and biochemical characterization of beta-1,3-N-acetylgalactosaminyltransferase LgtD from Haemophilus influenzae strain Rd. We further discuss the use of different hematopoietically derived regulatory cell populations, including regulatory B cells, regulatory macrophages, tolerogenic dendritic cells, and myeloid-derived suppressor cells, for the induction of transplantation tolerance in light of new clinical trials developing therapies with some of these populations. Using principles of crisis intervention and trauma theory, social workers and social work students placed in these agencies are benefiting both firefighters and community members served by the fire department.

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Health practices and survival among middle-aged residents of Japan: a ten-year follow-up cohort study of 9 towns in Gunma. We used a recently developed mild demineralization procedure, followed by immunohistochemical staining of frozen sections, to investigate cell patterns in the hindlimbs of MRL/l mice at various stages of arthritic disease. Recent work demonstrates that costimulatory molecules play a critical role for clonal deletion of autoreactive T cells in the thymus. The aim of the study was to estimate the incidence of malignant mesothelioma in Iceland 1965-1995, as malignant mesothelioma is considered an indicator of past asbestos exposure in the population.

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To evaluate the clinical outcome of children with traumatic hyphema treated on an outpatient basis. Neural activity underlying motor-action preparation and cognitive narrowing in approach-motivated goal states. Some observers maintain that the rigid behaviour which characterises the nursing process contradicts the intuitive nature and individualistic approaches which are fundamental to nursing practice (Benner 1984). On the problem of the etiology and clinical aspects of cancer of the gallbladder

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There is continued research regarding how this process is initiated and maintained and to what extent systemic dysfunction of the immune or autonomic nervous system may play a role. Protective effect of 17beta-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway. We report a case of passenger lymphocyte syndrome occurring after ABO-incompatible kidney transplant.

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The MFIS and FSS but not the MFSS showed high internal consistency and split-half reliability. Differential mismatch detection was accomplished irrespective of DNA sequence composition and mismatch identity. In the remaining retrospective studies, the recurrence rates were also acceptable. Improvements in survival after childhood cancer have increased emphasis on health-related quality of life (HRQoL) of survivors.

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Human muscle energetics during voluntary and electrically induced isometric contractions as measured by 31P NMR spectroscopy. Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report.

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Zein- based drug and biomedical delivery systems are discussed with special focus on current and potential application in controlled drug delivery systems, and tissue engineering. Clinical, serological, immunogenetic, and morphological data were collected retrospectively from medical records of 146 patients with cryoglobulinemic glomerulonephritis who underwent biopsies in 25 Italian centers and 34 cryoglobulinemic controls without renal involvement.

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Pre- and in-hospital delay in treatment and in-hospital mortality after acute myocardial infarction. The reproductive cycle of male uinta ground squirrels: some anatomical and biochemical correlates. The strikingly rapid transformation of the clinical aspect of syphilis, and its cause The specific aim of the present study was to study the relaxation of Hyperin in rat isolated basilar artery and identify the underlying cellular mechanisms.

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The changing patterns of psychotropic drug use may be caused by warnings against use of antipsychotics. THE WORKING CAPACITY OF DUODENAL ULCER PATIENTS LIVING IN CITIES AND VILLAGES Triptans have been safely and effectively used in the management of migraine for more than fifteen years, and it seems reasonable to wonder what would be the economic impact of moving a specific triptan to OTC availability.

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Our study shows that nearly all Danes were exposed to the six most common phthalates, to BPA, TCS, and BP-3, and to at least two of the parabens. In this study, we investigated localizations of these peptides by immunocytochemistry and AM mRNA by non-radioisotopic in situ hybridization followed by the streptavidin and biotin complex (ABC) method and catalyzed signal amplification (CSA) in the rat adrenal medulla and gastric mucosa. The more user friendly medical hypnosis can be, the more readily it will be accepted by patients and the medical community. Our findings suggest that Bayesian generalized linear models which allow for non-normality in estimation offer an attractive tool for researchers undertaking cost-effectiveness analyses.

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Glyoxalase I-type hemithioacetal isomerization reactivity of a mononuclear Ni(II) deprotonated amide complex. Randomised, parallel-group trial with intention-to-treat analysis. CBS deficiency is characterized by lens dislocation, skeletal abnormalities, neurologic disturbances and thromboembolism.

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Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refraction, keratometry, and corneal aberrations. Binding of 14-3-3beta to PTPH1 in vitro was abolished by pretreating PTPH1 with potato acid phosphatase and was greatly enhanced by pretreating with Cdc25C-associated protein kinase. Case report contribution on the question of multiple primary carcinomas Retransfection of mouse AIF into cells subjected to human AIF-specific siRNA revealed that only AIF imported into mitochondria could repress SGs and that redox-active domains of AIF, which are dispensable for its apoptogenic action, were required for SG inhibition.

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Clinically, the patient presented with diarrhoea (up to ten times a day) and malaise. However, association analyses of two polymorphisms suggest that the ER-alpha gene or a gene located close to the ER-alpha locus might be related to susceptibility of familial ovarian cancer without BRCA1 mutation.

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corticosterone) or energy reserves are believed to be involved, few studies have directly focused on the proximate cues influencing behaviours directly related to reproductive success. We mined conditioned media of four ovarian cancer cell lines (HTB75, TOV-112D, TOV-21G and RMUG-S) by two-dimensional liquid chromatography-mass spectrometry. The immunoperoxidase technique was used to study the expression of ER and other related proteins in six cases of ACC and two cases of ICC. HIV risk-reduction interventions must take into consideration the cause of homelessness, access to and participation in shelter services, and individual factors (such as the effects of sexual orientation and ethnicity) that frequently have not been systematically included in previous research. In this review, we summarize the findings of these investigations and highlight how this information is being integrated into multistep mutagenesis cascades that impact specific signal transduction pathways and synergistically lead to leukemic transformation.

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Localization of S-adenosylmethionine in Candida utilis by ultraviolet microscopy. A 2-year educational fellowship is described which teaches both the process and the discipline of medical/surgical device innovation. Patients with psychiatric disorders were found to show a high seroprevalence of Toxoplasma gondii infection.

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A-63-year-old man was referred to our hospital for interferon therapy to treat chronic hepatitis C. Microsatellite analysis to assess chromosome 18q status in colorectal cancer. Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs. As in our patient, it typically presents as indurated, tender plaques and nodules on the arms, thighs, and buttocks. It place role in detection of genetic abnormalities (in low pregnancies), prediction of outcomes growth-restricted fetuses, assessment of severity of heart failure due to congestive heart anomalies, fetal infections, hydrops fetalis.

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Influence of ovine growth hormone on water and NaCl absorption by the rat proximal jejunum and distal ileum. Elevated resistive index in the hepatic artery as a predictor of fulminant hepatic failure in patients with acute viral hepatitis: a prospective study using Doppler ultrasound.

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This paper reports a study exploring the strategies a group of mothers of overweight and obese children were using and planned to use in the future to assist their children to achieve a healthy weight. A critical function of the intestinal mucosa is to form a barrier that separates luminal contents from the underlying interstitium.

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Cervical cancer is one of the leading causes of death for middle-aged women in the developing world, yet it is almost completely preventable, if precancerous lesions are identified and treated in a timely manner. Currently, a consensus on the anesthetic technique of choice in those cases does not exist in the literature. Tyrosine sulfation is a posttranslational modification common in peptides and proteins synthesized by the secretory pathway in most eukaryotes. Minimal invasive endoscopic management of synchronous granular cell tumours in the colon and posterior mediastinum. Radiological extent of disease has been linked to early and late outcomes of anti-tuberculosis treatment, but no validated tools are available to quantify this parameter.

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In addition, PG adulterated with AS will lead a poor efficacy in clinical application. Loss of escape-related giant neurons in a spiny lobster, Panulirus argus. Markers for autophagy induction including LC3 conversion, suppression of mTOR pathway, and GFP-LC3 dot formation were enhanced by glutamate treatment. Health care utilization among older Mexicans: health and socioeconomic inequalities. STUDY BY ELECTRON MICROSCOPE OF THE NEUROSECRETORY CELLS OF THE INTERSTITIAL LATERO-DORSAL HYPOTHALAMIC NUCLEUS IN THE MALE GUINEA PIG

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Primary wound healing was achieved in 300 cases and delayed healing in 22 cases. Similar reaction is not observed in the stress-related bone injuries. Sister-chromatid exchanges (SCE) have been induced at concentrations as low as 7.5 mM. Evaluation of wood s light and direct smear for diagnosis of pityriasis versicolor and erythrasma.

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The potential relationship between serum CRP level and the presence and degree of carotid stenosis, as well as the strength of this association with traditionally established demographic, historical, and laboratory risk factors such as age, hypertension, and LDL-C level. To examine the association between aspirin use after colorectal cancer diagnosis on colorectal cancer-specific and overall survival. The decreased CMC of SDS in the presence of 2 is in accordance with its increased hydrophobicity due to the fluorinated side chain. Medline, PsycINFO, PubMed, and Web of Science searches were conducted using the keywords metabolic syndrome, syndrome x, central adiposity/obesity, visceral adiposity/obesity, body fat distribution, waist circumference, waist hip ratio, insulin resistance/sensitivity, glucose tolerance, psychological, depression, hostility, anger, cynicism, and anxiety. Pathohistology of costal cartilage and immunomorphologic characteristics of collagen in funnel chest

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CT data sets from a healthy subject were used for the VL studies. The results of this study suggest that Tl-201 scintigraphy is a powerful tool in the evaluation of tumor response to chemotherapy in patients with osteosarcoma. Body mass index is known to be positively associated with an increased risk of adenocarcinomas of the esophagus, yet there is there limited evidence on whether physical activity or sedentary behavior affects risk of histology- and site-specific upper gastrointestinal cancers. Results from ReFacto-treated anti-FVIII antibody-positive or -negative patients were compared with those for normal healthy adults and patients treated with other FVIII products.

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It was thus concluded that the P fimbriae recognize and bind to the alpha-D-Galp-(1-4)-beta-D-Galp carbohydrate sequence occurring in the series of P-blood group antigen-specific glycosphingolipids. This disease is associated with a progressive neurodegenerative course beginning at the age of two years with developmental stagnation, finally leading to a complete loss of motor function, vision and speech by the age of 10 years.

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Suicide risk is elevated in those suffering from chronic PTSD and is associated with impaired functioning in combination with depression. Recent prospective studies using colonoscopy have shown a 3 time higher prevalence of intestinal polyps and up to 4 time increased presence of colorectal cancer in acromegaly, independently of sex, age, duration of disease and clinical status of the patients. To determine the relationships between induction of COX-2 in the brain with IL-1beta- and LPS-induced changes in body temperature, plasma corticosterone and feeding.

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In addition, vein endothelial cells formed a linear, aligned vessel-like structure in this system. These results with glutamic acid differ from data reported by other investigators on the transport characteristics of glucose and neutral amino acids by brushborder membrane vesicles. The cellular inflammatory response in human spinal cords after injury. Epithelioid sarcoma is a rare malignant soft tissue tumor of unknown histogenesis, characterized by the epithelioid morphology of tumor cells and co-expression of epithelial and mesenchymal lineage proteins.

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The transcription factor Wilms tumor protein 1 (WT1) belongs to a new generation of tumor antigens, as it is essential for tumor cell proliferation and is highly expressed in various hematologic and solid malignancies. Urinary bladder carcinogenesis induced by chronic exposure to persistent low-dose ionizing radiation after Chernobyl accident. Number-wise, the pregnancies occurred most often in Israeli-born, high-school educated young women. Neither of studied variables was perfect to differentiate cirrhotic patients with and without EVs. The optimal EAdi-catheter position (OPT) was defined by: (1) stable EAdi signal, (2) electrical activity highlighted in central leads of the catheter positioning tool, and (3) absence of p-wave in distal lead.

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Aortic valve patch closure: an alternative to replacement with HeartMate LVAS insertion. The organ bath is a traditional experimental set-up that has been used extensively to investigate the (patho)physiology and pharmacology of in vitro tissue preparations including the rat carotid artery. Decomposition of perfluorocarboxylic acids (PFCAs) by heterogeneous photocatalysis in acidic aqueous medium.